Biyografi
K. Yalçın Arga is a professor of bioengineering and senior expert on
bioinformatics and multi-omics research. His research centers on statistical
and mathematical modeling and translation of Big Data to applications in
systems biology, pharmaceutical innovation, drug repositioning, health care, and
clinical practice. He is a frequent contributor to recognized international systems biology forums
as well as having authored works in high-impact journals such as Nature Biotechnology. His works are interdisciplinary and integrative, spanning
the continuum of metabolic systems engineering in bacteria to drug repurposing
and diagnostics innovation for common complex human diseases. His research currently focuses on translating multi-omics Big Data to clinical and
health care innovation. Professor Arga has also mentored numerous students who
have gone on to pursue productive careers as independent researchers in
academia and industry. Prof. Arga received his Bachelor's degree (B.Sc.) and Doctorate
(Ph.D.) in Chemical Engineering from Boğaziçi University in Istanbul. He is currently Professor of Bioengineering at the Department of Bioengineering at Marmara University Istanbul, Turkey. Professor Arga is a frequently sought
after the referee in the field of systems biology, bioinformatics, and
bioengineering and a frequent presenter at international conferences.
Eğitim Bilgileri
2002 - 2007
2002 - 2007Doktora
Boğaziçi Üniversitesi, Fen Bilimleri Enstitüsü, Kimya Mühendisliği (Dr), Türkiye
2001 - 2002
2001 - 2002Yüksek Lisans
Boğaziçi Üniversitesi, Fen Bilimleri Enstitüsü, Kimya Mühendisliği (Yl) (Tezli), Türkiye
1997 - 2001
1997 - 2001Lisans
Boğaziçi Üniversitesi, Mühendislik Fakültesi, Kimya Mühendisliği Bölümü, Türkiye
Yaptığı Tezler
2007
2007Doktora
Systems biology of yeast signal transduction
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
Yabancı Diller
C2 Ustalık
C2 Ustalıkİngilizce
Araştırma Alanları
Biyoistatistik ve Tıp Bilişimi
Biyokimya
Tıbbi Biyoloji
Biyomedikal Mühendisliği
Klinik Mühendisliği
Biyoteknoloji
Biyokimyasal Reaksiyon Mühendisliği
Biyomedikal Mühendislik
Biyoteknolojik Prosesler ve Fermentasyon Teknolojisi
Metabolik Mühendislik
Akademik Ünvanlar / Görevler
2020 - Devam Ediyor
2020 - Devam EdiyorProf. Dr.
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
2015 - 2020
2015 - 2020Doç. Dr.
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
2007 - 2015
2007 - 2015Yrd. Doç. Dr.
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
2001 - 2007
2001 - 2007Araştırma Görevlisi
Boğaziçi Üniversitesi, Mühendislik Fakültesi, Kimya Mühendisliği Bölümü
Yönetimsel Görevler
2022 - Devam Ediyor
2022 - Devam EdiyorSoruşturma Komisyonu Üyesi
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
2022 - Devam Ediyor
2022 - Devam EdiyorBölüm Başkan Yardımcısı
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
2018 - Devam Ediyor
2018 - Devam EdiyorBölüm Akademik Teşvik Değerlendirme Komisyonu Üyesi
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
2019 - 2021
2019 - 2021Akademisyen
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
2019 - 2020
2019 - 2020Ar-Ge Direktörü
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
2012 - 2019
2012 - 2019Bölüm Başkan Yardımcısı
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
2010 - 2019
2010 - 2019Bölüm Tanıtım ve Mezunlarla İlişkiler Komisyonu Başkanı
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
2015 - 2018
2015 - 2018Bölüm Akademik Teşvik Değerlendirme Komisyonu Üyesi
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
2015 - 2018
2015 - 2018Fakülte Yönetim Kurulu Üyesi
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
2014 - 2017
2014 - 2017Fakülte Kurulu Üyesi
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
2010 - 2013
2010 - 2013Birim Tanıtım ve Mezunlarla İlişkiler Komisyonu Üyesi
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
2008 - 2009
2008 - 2009Bölüm Başkan Yardımcısı
Marmara Üniversitesi, Mühendislik Fakültesi, Biyomühendislik Bölümü
Akademi Dışı Deneyim
2021 - Devam Ediyor
2021 - Devam EdiyorDanışma Kurulu Üyesi
TÜBİTAK, ARDEB, -, Danışma Kurulu Üyesi
2013 - Devam Ediyor
2013 - Devam EdiyorKOSGEB Teknik Danışman ve İzleyici
Diğer Kamu Kurumu, KOSGEB, -, KOSGEB Teknik Danışman ve İzleyici
2019 - 2021
2019 - 2021AKADEMİSYEN
TÜRKİYE SAĞLIK ENSTİTÜLERİ BAŞKANLIĞI, AKADEMİSYEN
Verdiği Dersler
Doktora
Advanced Topics in Bioengineering I
Toksikoloji
Biological Networks Theory
Endüstriyel Hijyen ve Enstrümentasyon
Yüksek Lisans
Biostatistics
Engineering Medicine
Endüstriyel Hijyen ve Toksikoloji
Dönem Projesi
Mathematical Modeling in Biological Systems
System Biology
Advanced Bioinformatics
Lisans
Introduction to Bioengineering
Bioprocess Dynamics and Control
Scientific Programming
Bioengineering Project II
Introduction to Systems Biology
Mathematical Applications in Bioengineering Systems
Biostatistics
Business in a Competitive Environment in Bioengineering
Bioengineering Principles
Bioengineering Project I
Yönetilen Tezler
2019
2019Yüksek Lisans
Differential co-expression analysis of human cancers to reveal systems biomarkers for diagnostic and therapeutic trials
ARĞA K. Y. (Danışman)
M.Nur(Öğrenci)
2019
2019Yüksek Lisans
Reconstruction of tissue-specific protein-protein interaction sub-networks to improve prediction accuracy of bioinformatics tools
ARĞA K. Y. (Danışman)
N.Çakır(Öğrenci)
2018
2018Doktora
Systems biomedicine and pharmacology approaches for drug repositioning to uncover candidate anti-cancer drugs
ARĞA K. Y. (Danışman)
B.TURANLI(Öğrenci)
2018
2018Yüksek Lisans
Dynamic mapping of protein interactions in cancer
ARĞA K. Y. (Danışman)
G.GÜLFİDAN(Öğrenci)
2017
2017Doktora
Systems biology approaches to identify novel biomarkers for diagnosis, prognosis and therapeutics in ovarian cancer
ARĞA K. Y. (Danışman)
E.GÖV(Öğrenci)
2017
2017Doktora
Brevibacillus thermoruber as a microbial cell factory
ARĞA K. Y. (Danışman)
S.YAŞAR(Öğrenci)
2016
2016Yüksek Lisans
Analysis of dose rate-tumor response with a mathematical model in treatment of intracranial metastases with Gamma Knife Radiosurgery
ARĞA K. Y. (Danışman)
A.FİDAN(Öğrenci)
2015
2015Doktora
Systematic and integrative analysis of breast cancer and other associated diseases using transcriptome data and interactome networks
ARĞA K. Y. (Danışman)
K.KARAGÖZ(Öğrenci)
2015
2015Yüksek Lisans
Computational prediction of genomic and proteomic biomarker candidates for reproductive system associated women diseases
ARĞA K. Y. (Danışman)
M.KORİ(Öğrenci)
2015
2015Doktora
Using systems based models to uncover the disease network of Psoriasis and its associations with other autoimmune-related diseases
ARĞA K. Y. (Danışman)
T.SEVİMOĞLU(Öğrenci)
2014
2014Yüksek Lisans
Purification and characterization of levansucrase by Halomonas smyrnensis AAD6T
ARĞA K. Y. (Danışman)
B.ÇALIMLIOĞLU(Öğrenci)
2014
2014Yüksek Lisans
Investigation of the fructose uptake system in halomonas smyrnensis AAD6 to design strategies for enhanced levan biosynthesis
ARĞA K. Y. (Danışman)
B.AYDIN(Öğrenci)
2013
2013Yüksek Lisans
Bioinformatics based metabolic network reconstruction of levan producing Halomonas smyrnensis AAD6
ARĞA K. Y. (Danışman)
T.ÖZER(Öğrenci)
2012
2012Yüksek Lisans
Whole genome sequencing and genome annotation of levan producing Halomonas smyrnensis AAD6
ARĞA K. Y. (Danışman)
E.SÖĞÜTCÜ(Öğrenci)
Araştırma Altyapısı Bilgileri
Ocak 2011
Ocak 2011Hesaplamalı Biyoloji ve Biyoinformatik Laboratuvarı
İleri Araştırma Laboratuvarı - Sorumlu Yöneticilik
Arğa K. Y., Özbek Sarıca P.
Ocak 2011
Ocak 2011Systems Bioengineering Laboratory
İleri Araştırma Laboratuvarı - Sorumlu Yöneticilik
Arğa K. Y.
Ocak 2008
Ocak 2008Industrial Biotechnology and Systems Biology Laboratory
İleri Araştırma Laboratuvarı - Sorumlu Yöneticilik
Arğa K. Y., Toksoy Öner E.
Eğitim Altyapısı Bilgileri
Tasarlanan Programlar
Makaleler
2025
20251. HBV Infection Drives PSMB5-Dependent Proteasomal Activation in Humanized Mice and HBV-Associated HCC
JANNUZZI A. T., Sari G., Arslan-Eseryel S., Zeybel M., YILMAZ Y., DAYANGAÇ M., et al.
Viruses
, cilt.17, sa.11, 2025 (SCI-Expanded, Scopus)
2025
20252. Analysis of miRNA Expression Profiles in High Cholesterol Diet-Induced MASH Progression: Potential Effect of α-Tocopherol
Demirel-Yalciner T., Cetinkaya B., ARGA K. Y., SÖZEN A. E., Ozer N. K.
IUBMB Life
, cilt.77, sa.9, 2025 (SCI-Expanded)
2025
20253. A Pilot Investigation of Circulating miRNA Expression in Individuals Exposed to Aluminum and Welding Fumes
Öztan G., İşsever H., İşsever T., Oğuz F., CANBAZ S., Küçükgergin C., et al.
Current Issues in Molecular Biology
, cilt.47, sa.5, 2025 (SCI-Expanded)
2025
20254. Casticin inhibits the hedgehog signaling and leads to apoptosis in AML stem-like KG1a and mature KG1 cells
Erkmen Doǧru T., Gülfidan G., ATEŞ H., ARGA K. Y., KOÇTÜRK A. S.
Turkish Journal of Biochemistry
, cilt.50, sa.1, ss.62-72, 2025 (SCI-Expanded)
2025
20255. A Health-Sector-Specific Occupational Health and Safety Management System Model
Yeşilgöz P., ARGA K. Y.
Healthcare (Switzerland)
, cilt.13, sa.3, 2025 (SCI-Expanded)
2024
20246. Cytokine Signature Differences in Major Phenotypic Groups of Behçet Disease
Deniz R., EMRENCE Z., Punar Ş., İleri B., ARGA K. Y., ALİBAZ ÖNER F., et al.
Journal of Clinical Rheumatology
, cilt.30, sa.8, 2024 (SCI-Expanded, Scopus)
2024
20247. Public health challenges after the February 6 earthquakes: A comprehensive review of immediate and long-term impacts in Türkiye
Koçer A. T., Akpek A., Vural A., Aslan A., Erkoç A., Özen A. M., et al.
International Journal of Disaster Risk Reduction
, cilt.114, 2024 (SCI-Expanded)
2024
20248. Exploring COVID-19 Pandemic Disparities with Transcriptomic Meta-analysis from the Perspective of Personalized Medicine
Kori M., KASAVİ C., ARGA K. Y.
Journal of Microbiology
, cilt.62, sa.9, ss.785-798, 2024 (SCI-Expanded)
2024
20249. Tumor Mutation Burden as a Cornerstone in Precision Oncology Landscapes: Effect of Panel Size and Uncertainty in Cutoffs
Budak B., ARGA K. Y.
OMICS A Journal of Integrative Biology
, cilt.28, sa.4, ss.193-203, 2024 (SCI-Expanded)
2024
202410. Genome-scale metabolic models in translational medicine: the current status and potential of machine learning in improving the effectiveness of the models
TURANLI B., Gulfidan G., Aydogan O. O., KULA C., Selvaraj G., ARGA K. Y.
Molecular Omics
, cilt.20, sa.4, ss.234-247, 2024 (SCI-Expanded)
2024
202411. A 19-Gene Signature of Serous Ovarian Cancer Identified by Machine Learning and Systems Biology: Prospects for Diagnostics and Personalized Medicine
Kori M., Demirtas T. Y., Comertpay B., ARGA K. Y., Sinha R., Gov E.
OMICS A Journal of Integrative Biology
, cilt.28, sa.2, ss.90-101, 2024 (SCI-Expanded)
2024
202412. Biomarkers From Discovery to Clinical Application: In Silico Pre-Clinical Validation Approach in the Face of Lung Cancer
KORİ M., Gov E., ARGA K. Y., Sinha R.
Biomarker Insights
, cilt.19, 2024 (ESCI)
2024
202413. Pharmacomicrobiomics-Guided Precision Oncology: A New Frontier of P4 (Predictive, Personalized, Preventive, and Participatory) Medicine and Microbiome-Based Therapeutics
ARGA K. Y., Attia H., Aziz R. K.
Omics : a journal of integrative biology
, cilt.28, sa.1, ss.5-7, 2024 (SCI-Expanded)
2023
202314. Differential co-expression network analysis elucidated genes associated with sensitivity to farnesyltransferase inhibitor and prognosis of acute myeloid leukemia
Kelesoglu N., Kori M., Yilmaz B. K., Duru O. A., ARGA K. Y.
Cancer Medicine
, cilt.12, sa.24, ss.22420-22436, 2023 (SCI-Expanded)
2023
202315. A Differential Transcriptional Regulome Approach to Unpack Cancer Biology: Insights on Renal Cell Carcinoma Subtypes
Caliskan A., ARGA K. Y.
OMICS A Journal of Integrative Biology
, cilt.27, sa.11, ss.536-545, 2023 (SCI-Expanded)
2023
202316. Three candidate anticancer drugs were repositioned by integrative analysis of the transcriptomes of species with different regenerative abilities after injury
Kubat Oktem E., Demir U., Yazar M., ARGA K. Y.
Computational Biology and Chemistry
, cilt.106, 2023 (SCI-Expanded)
2023
202317. Toward Precision Oncology in Glioblastoma with a Personalized Cancer Genome Reporting Tool and Genetic Changes Identified by Whole Exome Sequencing
ERDOĞAN O., Özkaya Ş. Ç., ERZİK C., Bilguvar K., ARGA K. Y., BAYRAKLI F.
Omics : a journal of integrative biology
, cilt.27, sa.9, ss.426-433, 2023 (SCI-Expanded, Scopus)
2023
202318. The Versatility of Plectin in Cancer: A Pan-Cancer Analysis on Potential Diagnostic and Prognostic Impacts of Plectin Isoforms
Gundesli H., Kori M., ARGA K. Y.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, cilt.27, sa.6, ss.281-296, 2023 (SCI-Expanded)
2023
202319. HPV16 status predicts potential protein biomarkers and therapeutics in head and neck squamous cell carcinoma
Kori M., ARĞA K. Y.
Virology
, cilt.582, ss.90-99, 2023 (SCI-Expanded)
2023
202320. Systems Biomarkers, Artificial Intelligence, and One Health Vision Can Help Fight Antimicrobial Resistance
KULA C., ARĞA K. Y.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, cilt.27, sa.4, ss.191-192, 2023 (SCI-Expanded)
2023
202321. A Transcriptomic and Reverse-Engineering Strategy Reveals Molecular Signatures of Arachidonic Acid Metabolism in 12 Cancers
KUBAT ÖKTEM E., Aydin B., Gulfidan G., ARĞA K. Y.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, cilt.27, sa.3, ss.127-138, 2023 (SCI-Expanded)
2023
202322. Potential Early Markers for Breast Cancer: A Proteomic Approach Comparing Saliva and Serum Samples in a Pilot Study
Sinha I., Fogle R. L., Gulfidan G., Stanley A. E., Walter V., Hollenbeak C. S., et al.
International Journal of Molecular Sciences
, cilt.24, sa.4, 2023 (SCI-Expanded)
2023
202323. Editorial: Omics integration and network medicine to decipher human complex diseases
Zanfardino M., Babbi G., ARĞA K. Y., Pane K.
Frontiers in Genetics
, cilt.14, 2023 (SCI-Expanded)
2022
202224. Integrative Analysis of Motor Neuron and Microglial Transcriptomes from SOD1(G93A) Mice Models Uncover Potential Drug Treatments for ALS
KUBAT ÖKTEM E., Aydin B., Yazar M., ARĞA K. Y.
JOURNAL OF MOLECULAR NEUROSCIENCE
, cilt.72, sa.11, ss.2360-2376, 2022 (SCI-Expanded)
2022
202225. Human oncogenic viruses: an overview of protein biomarkers in viral cancers and their potential use in clinics
Kori M., ARĞA K. Y.
EXPERT REVIEW OF ANTICANCER THERAPY
, cilt.22, sa.11, ss.1211-1224, 2022 (SCI-Expanded)
2022
202226. A Pan-Cancer Atlas of Differentially Interacting Hallmarks of Cancer Proteins
Kori M., Ozdemir G. E., ARĞA K. Y., Sinha R.
JOURNAL OF PERSONALIZED MEDICINE
, cilt.12, sa.11, 2022 (SCI-Expanded)
2022
202227. Precision Oncology: An Ensembled Machine Learning Approach to Identify a Candidate mRNA Panel for Stratification of Patients with Breast Cancer
Kurt F., AĞAOĞLU M., ARĞA K. Y.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, cilt.26, ss.504-511, 2022 (SCI-Expanded)
2022
202228. Acute Myeloid Leukemia: New Multiomics Molecular Signatures and Implications for Systems Medicine Diagnostics and Therapeutics Innovation
Kelesoglu N., Kori M., TURANLI B., ARĞA K. Y., Yilmaz B., Duru O. A.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, cilt.26, sa.7, ss.392-403, 2022 (SCI-Expanded)
2022
202229. Repositioning of Anti-Inflammatory Drugs for the Treatment of Cervical Cancer Sub-Types
Kori M., ARĞA K. Y., Mardinoglu A., TURANLI B.
FRONTIERS IN PHARMACOLOGY
, cilt.13, 2022 (SCI-Expanded)
2022
202230. Driving Precision Oncology to Clinical Practice: The Road Ahead from Biomarker Validation to Clinical Decision Systems
Yilmaz B., ARĞA K. Y.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, cilt.26, sa.6, ss.358-359, 2022 (SCI-Expanded)
2022
202231. Multiomics Data Integration Identifies New Molecular Signatures for Abdominal Aortic Aneurysm and Aortic Occlusive Disease: Implications for Early Diagnosis, Prognosis, and Therapeutic Targets
Kori M., Cig D., Arga K. Y., Kasavi C.
OMICS A JOURNAL OF INTEGRATIVE BIOLOGY
, cilt.26, sa.5, ss.1-15, 2022 (SCI-Expanded)
2022
202232. Precision Diagnosis of Maturity-Onset Diabetes of the Young with Next-Generation Sequencing: Findings from the MODY-IST Study in Adult Patients
Aydogan H. Y., Gul N., Demirci D. K., Mutlu U., Gulfidan G., ARĞA K. Y., et al.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, cilt.26, ss.218-235, 2022 (SCI-Expanded)
2022
202233. Past, Present, and Future of Therapies for Pituitary Neuroendocrine Tumors: Need for Omics and Drug Repositioning Guidance
Aydin B., Yildirim E., ERDOĞAN O., ARĞA K. Y., Yilmaz B., BOZKURT S., et al.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, cilt.26, sa.3, ss.115-129, 2022 (SCI-Expanded)
2022
202234. MicroRNA-Mediated Drug Repurposing Unveiled Potential Candidate Drugs for Prolactinoma Treatment
Aydin B., Arslan S., BAYRAKLI F., YILMAZ B., ARĞA K. Y.
NEUROENDOCRINOLOGY
, cilt.112, ss.161-173, 2022 (SCI-Expanded)
2022
202235. Systems biomarkers for papillary thyroid cancer prognosis and treatment through multi-omics networks
Gulfidan G., Soylu M., Demirel D., Erdonmez H. B. C., Beklen H., ÖZBEK SARICA P., et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
, cilt.715, 2022 (SCI-Expanded, Scopus)
2022
202236. Decreased serum levels of glycerol-3-phosphate dehydrogenase 1 and monoacylglycerol lipase act as diagnostic biomarkers for breast cancer
KARAOSMANOĞLU YÖNETEN K., KASAP M., ARĞA K. Y., AKPINAR G., UTKAN N. Z.
CANCER BIOMARKERS
, cilt.34, sa.1, ss.67-76, 2022 (SCI-Expanded)
2021
202137. Artificial Intelligence as Accelerator for Genomic Medicine and Planetary Health
Gulfidan G., Beklen H., ARĞA K. Y.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, cilt.25, ss.745-749, 2021 (SCI-Expanded)
2021
202138. Lower COVID-19 Mortality in Patients with Type 2 Diabetes Mellitus Taking Dipeptidyl Peptidase-4 Inhibitors: Results from a Turkish Nationwide Study
Emral R., Haymana C., Demirci I., Tasci I., Sahin M., Cakal E., et al.
DIABETES THERAPY
, cilt.12, sa.11, ss.2857-2870, 2021 (SCI-Expanded)
2021
202139. Differential Interactome Based Drug Repositioning Unraveled Abacavir, Exemestane, Nortriptyline Hydrochloride, and Tolcapone as Potential Therapeutics for Colorectal Cancers
beklen h., arslan s., Gulfidan G., Turanlı B., ÖZBEK SARICA P., Karademir Yılmaz B., et al.
Frontiers in Bioinformatics
, cilt.1, 2021 (Hakemli Dergi)
2021
202140. Overview of omics biomarkers in pituitary neuroendocrine tumors to design future diagnosis and treatment strategies
Aydin B., Caliskan A., ARĞA K. Y.
EPMA JOURNAL
, cilt.12, sa.3, ss.383-401, 2021 (SCI-Expanded)
2021
202141. Differential Protein Interactome in Esophageal Squamous Cell Carcinoma Offers Novel Systems Biomarker Candidates with High Diagnostic and Prognostic Performance
Gulfidan G., Beklen H., Sinha I., Kucukalp F., Caloglu B., Esen I., et al.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, cilt.25, ss.495-512, 2021 (SCI-Expanded)
2021
202142. Thanatechnology and the Living Dead: New Concepts in Digital Transformation and Human-Computer Interaction
Ozdemir V., Springer S., YILDIRIM A., Bicer S., Kendirci A., Sardas S., et al.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, cilt.25, ss.401-407, 2021 (SCI-Expanded)
2021
202143. Monogenic Childhood Diabetes: Dissecting Clinical Heterogeneity by Next-Generation Sequencing in Maturity-Onset Diabetes of the Young
Demirci D. K., Darendeliler F., Poyrazoglu S., Al A. D. K., GÜL N., Tutuncu Y., et al.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, cilt.25, ss.431-449, 2021 (SCI-Expanded)
2021
202144. Systems-level biomarkers identification and drug repositioning in colorectal cancer
Beklen H., Yildirim E., Kori M., TURANLI B., ARĞA K. Y.
WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY
, cilt.13, sa.7, ss.638-661, 2021 (SCI-Expanded)
2021
202145. Cancer Stem Cell Transcriptome Profiling Reveals Seed Genes of Tumorigenesis: New Avenues for Cancer Precision Medicine
Comertpay B., Gulfidan G., ARĞA K. Y., Gov E.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, cilt.25, ss.372-388, 2021 (SCI-Expanded)
2021
202146. Unexpectedly lower mortality rates in COVID-19 patients with and without type 2 diabetes in Istanbul
Satman I., Demirci I., Haymana C., Tasci I., Salman S., Ata N., et al.
DIABETES RESEARCH AND CLINICAL PRACTICE
, cilt.174, 2021 (SCI-Expanded)
2021
202147. Recent Developments in Cancer Systems Biology: Lessons Learned and Future Directions
ARĞA K. Y., Sinha R.
JOURNAL OF PERSONALIZED MEDICINE
, cilt.11, sa.4, 2021 (SCI-Expanded)
2021
202148. The Repertoire of Glycan Alterations and Glycoproteins in Human Cancers.
Kori M., Aydin B., Gulfidan G., Beklen H., Kelesoglu N., Caliskan Iscan A., et al.
Omics : a journal of integrative biology
, cilt.25, sa.3, ss.139-168, 2021 (SCI-Expanded)
2021
202149. ETS-Domain Transcription Factor Elk-1 Regulates Stemness Genes in Brain Tumors and CD133+ BrainTumor-Initiating Cells
SÖĞÜT M. S., Venugopal C., KANDEMİR B., Dag U., Mahendram S., Singh S., et al.
JOURNAL OF PERSONALIZED MEDICINE
, cilt.11, sa.2, 2021 (SCI-Expanded)
2021
202150. Differential Interactome Proposes Subtype-Specific Biomarkers and Potential Therapeutics in Renal Cell Carcinomas
Caliskan A., Gulfidan G., Sinha R., ARĞA K. Y.
JOURNAL OF PERSONALIZED MEDICINE
, cilt.11, sa.2, 2021 (SCI-Expanded)
2021
202151. Current State of "Omics" Biomarkers in Pancreatic Cancer
TURANLI B., Yildirim E., Gulfidan G., ARĞA K. Y., Sinha R.
JOURNAL OF PERSONALIZED MEDICINE
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2021
202152. Systems biology based drug repositioning for development of cancer therapy.
Turanli B., Altay O., Borén J., Turkez H., Nielsen J., Uhlen M., et al.
Seminars in cancer biology
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2020
202053. Integrative transcriptomics analysis of lung epithelial cells and identification of repurposable drug candidates for COVID-19
Islam T., Rahman M. R., Aydin B., Beklen H., ARĞA K. Y., Shahjaman M.
EUROPEAN JOURNAL OF PHARMACOLOGY
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2020
202054. Pathways involved in viral oncogenesis: New perspectives from virus-host protein interactomics
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BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
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2020
202055. Comprehensive Analysis of RNA-Seq Gene Expression Profiling of Brain Transcriptomes Reveals Novel Genes, Regulators, and Pathways in Autism Spectrum Disorder
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BRAIN SCIENCES
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2020
202056. Transcriptomic profile of Pea3 family members reveal regulatory codes for axon outgrowth and neuronal connection specificity
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SCIENTIFIC REPORTS
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2020
202057. COVID-19 and the Futures of Machine Learning
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OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
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2020
202058. Novel molecular signatures and potential therapeutics in renal cell carcinomas: Insights from a comparative analysis of subtypes
Caliskan A., Andac A. C., ARĞA K. Y.
GENOMICS
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2020
202059. Drug Repositioning for P-Glycoprotein Mediated Co-Expression Networks in Colorectal Cancer
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FRONTIERS IN ONCOLOGY
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2020
202060. Higher proteotoxic stress rather than mitochondrial damage is involved in higher neurotoxicity of bortezomib compared to carfilzomib
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REDOX BIOLOGY
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2020
202061. New Machine Learning Applications to Accelerate Personalized Medicine in Breast Cancer: Rise of the Support Vector Machines
Ozer M. E., Sarica P., ARĞA K. Y.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
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2020
202062. Mapping the Molecular Basis and Markers of Papillary Thyroid Carcinoma Progression and Metastasis Using Global Transcriptome and microRNA Profiling.
Akyay O., Gov E., Kenar H., Arga K. Y., Selek A., Tarkun İ., et al.
Omics : a journal of integrative biology
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2020
202063. Digging Deeper into Precision/Personalized Medicine: Cracking the Sugar Code, the Third Alphabet of Life, and Sociomateriality of the Cell.
Özdemir V., Arga K. Y., Aziz R., Bayram M., Conley S., Dandara C., et al.
Omics : a journal of integrative biology
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2020
202064. Pan-cancer mapping of differential protein-protein interactions
Gulfidan G., Turanli B., Beklen H., Sinha R., Arga K. Y.
SCIENTIFIC REPORTS
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2020
202065. Omics-Driven Biomarkers of Psoriasis: Recent Insights, Current Challenges, and Future Prospects
Aydin B., ARĞA K. Y., KARADAĞ A. S.
CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY
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2019
201966. Interview with Prof. K. Yalçın Arga: A Pioneer of Multi-Omics Science and Health Care Innovation.
Arga K. Y.
Omics : a journal of integrative biology
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2019
201967. Cancer Drug Repositioning by Comparison of Gene Expression in Humans and Axolotl (<i>Ambystoma mexicanum</i>) During Wound Healing.
Öktem E., Yazar M., Gulfidan G., Arga K. Y.
Omics : a journal of integrative biology
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2019
201968. Co-expression Network Analysis Elucidated a Core Module in Association With Prognosis of Non-functioning Non-invasive Human Pituitary Adenoma.
Aydin B., Arga K. Y.
Frontiers in endocrinology
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2019
201969. Multi-Omic Data Interpretation to Repurpose Subtype Specific Drug Candidates for Breast Cancer
Turanli B., Karagoz K., Bidkhori G., Sinha R., Gatza M., Uhlen M., et al.
FRONTIERS IN GENETICS
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2019
201970. Novel Genomic Biomarker Candidates for Cervical Cancer As Identified by Differential Co-Expression Network Analysis.
Kori M., Gov E., Arga K. Y.
Omics : a journal of integrative biology
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2019
201971. Identification of Novel Components of Target-of-Rapamycin Signaling Pathway by Network-Based Multi-Omics Integrative Analysis
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OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
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2019
201972. Discovery of therapeutic agents for prostate cancer using genome-scale metabolic modeling and drug repositioning
Turanli B., Zhang C., Kim W., Benfeitas R., Uhlen M., Arga K. Y., et al.
EBIOMEDICINE
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2019
201973. Network-based approach to identify molecular signatures and therapeutic agents in Alzheimer's disease
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COMPUTATIONAL BIOLOGY AND CHEMISTRY
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2019
201974. Identification of Prognostic Biomarker Signatures and Candidate Drugs in Colorectal Cancer: Insights from Systems Biology Analysis
Rahman M. R., Islam T., Gov E., Turanli B., Gulfidan G., Shahjaman M., et al.
MEDICINA-LITHUANIA
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2018
201875. Potential biomarkers and therapeutic targets in cervical cancer: Insights from the meta-analysis of transcriptomics data within network biomedicine perspective
Kori M., ARĞA K. Y.
PLOS ONE
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2018
201876. Exopolysaccharides Synthesized by Thermophilic MicroorganismsIsolated from Bulgarian Hot Springs
KAMBOUROVA M., RADCHENKOVA N., NICOLAUS B., TOMMONARO G., POLI A., TOKSOY ÖNER E., et al.
Acta Microbiologica Bulgarica , cilt.34, ss.68-76, 2018 (Scopus)
2018
201877. Drug Targeting and Biomarkers in Head and Neck Cancers: Insights from Systems Biology Analyses
İSLAM T., RAHMAN R., GÖV E., TURANLI B., GÜLFİDAN G., HAQUE M. A., et al.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
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2018
201878. Drug Repositioning for Effective Prostate Cancer Treatment
TURANLI B., Grotli M., BOREN J., NIELSEN J., UHLEN M., ARĞA K. Y., et al.
FRONTIERS IN PHYSIOLOGY
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2018
201879. Systems biomarkers in psoriasis: Integrative evaluation of computational and experimental data at transcript and protein levels
Sevimoglu T., Turanli B., Bereketoglu C., ARĞA K. Y., KARADAĞ A. S.
GENE
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2018
201880. The Genome-Based Metabolic Systems Engineering to Boost Levan Production in a Halophilic Bacterial Model
Aydin B., Ozer T., Oner E. T., ARĞA K. Y.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
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2018
201881. A Network-Based Cancer Drug Discovery: From Integrated Multi-Omics Approaches to Precision Medicine
TURANLI B., Karagoz K., Gulfidan G., Sinha R., Mardinoglu A., ARĞA K. Y.
CURRENT PHARMACEUTICAL DESIGN
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2017
201782. Transcriptomic-Guided Drug Repositioning Supported by a New Bioinformatics Search Tool: geneXpharma
Turanli B., Gulfidan G., ARĞA K. Y.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
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2017
201783. Multiomics Analysis of Tumor Microenvironment Reveals Gata2 and miRNA-124-3p as Potential Novel Biomarkers in Ovarian Cancer
Gov E., Kori M., ARĞA K. Y.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
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2017
201784. Genome reprogramming in Saccharomyces cerevisiae upon nonylphenol exposure
Bereketoglu C., ARĞA K. Y., Eraslan S., MERTOĞLU B.
PHYSIOLOGICAL GENOMICS
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2017
201785. Systems Biomedicine Acts as a Driver for the Evolution of Pharmacology
TURANLI B., ARĞA K. Y.
Annals of Pharmacology and Pharmaceutics , cilt.2, ss.1087-1088, 2017 (Hakemli Dergi)
2017
201786. Transcriptomic analysis displays the effect of (-)-roemerine on the motility and nutrient uptake in Escherichia coli
Ayyildiz D., ARĞA K. Y., Avci F. G., ALTINIŞIK KAYA F. E., Gurer C., Toplan G. G., et al.
CURRENT GENETICS
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2017
201787. Differential co-expression analysis reveals a novel prognostic gene module in ovarian cancer
Gov E., ARĞA K. Y.
SCIENTIFIC REPORTS
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2017
201788. Hypothesis: Are There Molecular Signatures of Yoga Practice in Peripheral Blood Mononuclear Cells?
Ayyildiz D., ARĞA K. Y.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
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2017
201789. Ovarian Cancer Differential Interactome and Network Entropy Analysis Reveal New Candidate Biomarkers
Ayyildiz D., Gov E., Sinha R., ARĞA K. Y.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
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2017
201790. Analysis of transcriptional profiles of Saccharomyces cerevisiae exposed to bisphenol A
Bereketoglu C., ARĞA K. Y., Eraslan S., MERTOĞLU B.
CURRENT GENETICS
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2017
201791. Multiomics Approach to Novel Therapeutic Targets for Cancer and Aging-Related Diseases: Role of Sld7 in Yeast Aging Network
Dayan I. E., ARĞA K. Y., Ulgen K. O.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
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2017
201792. RNA-based ovarian cancer research from 'a gene to systems biomedicine' perspective
Gov E., Kori M., ARĞA K. Y.
SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE
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2016
201693. Interactive cooperation and hierarchical operation of microRNA and transcription factor crosstalk in human transcriptional regulatory network
Gov E., ARĞA K. Y.
IET SYSTEMS BIOLOGY
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2016
201694. Metabolic Biomarkers and Neurodegeneration: A Pathway Enrichment Analysis of Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis
Kori M., Aydin B., ÜNAL S., ARĞA K. Y., KAZAN D.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
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2016
201695. Integration of multiple biological features yields high confidence human protein interactome
Karagoz K., Sevimoglu T., ARĞA K. Y.
JOURNAL OF THEORETICAL BIOLOGY
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2016
201696. Molecular signatures of ovarian diseases: Insights from network medicine perspective
Kori M., Gov E., ARĞA K. Y.
SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE
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2016
201697. Investigating the toxic effects of nonylphenol on Saccharomyces cerevisiae
Bereketoglu C., ARĞA K. Y., MERTOĞLU B.
NEW BIOTECHNOLOGY
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2016
201698. Systems biology perspective on diabetic nephropathy may reveal molecular mechanism of diabetic retinopathy
Calimlioglu B., Ozturk R., Arga K.
NEW BIOTECHNOLOGY
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2016
201699. "Omics" of Selenium Biology: A Prospective Study of Plasma Proteome Network Before and After Selenized-Yeast Supplementation in Healthy Men
Sinha I., Karagoz K., Fogle R. L., Hollenbeak C. S., Zea A. H., ARĞA K. Y., et al.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, cilt.20, sa.4, ss.202-213, 2016 (SCI-Expanded)
2016
2016100. Cardiomyogenic differentiation potential of human lipoaspirate-derived stem cells on hyaluronic acid/gelatin plasma gels
GÖV E., KENAR H., HALBUTOĞULLARI Z. S., ARĞA K. Y., KARAÖZ E.
TURKISH JOURNAL OF BIOLOGY
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2016
2016101. Proteomic and Metabolic Signatures of Esophageal Squamous Cell Carcinoma
KARAGÖZ K., LEHMAN H. L., STAİRS D. B., SİNHA R., ARĞA K. Y.
CURRENT CANCER DRUG TARGETS
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2015
2015102. Computational Systems Biology of Psoriasis: Are We Ready for the Age of Omics and Systems Biomarkers?
Sevimoglu T., ARĞA K. Y.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
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2015
2015103. Tissue-Specific Molecular Biomarker Signatures of Type 2 Diabetes: An Integrative Analysis of Transcriptomics and Protein-Protein Interaction Data
Calimlioglu B., Karagoz K., Sevimoglu T., Kilic E., Gov E., ARĞA K. Y.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
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2015
2015104. Genomic analysis reveals the biotechnological and industrial potential of levan producing halophilic extremophile, Halomonas smyrnensis AAD6T
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SPRINGERPLUS
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2015
2015105. Effective stimulating factors for microbial levan production by Halomonas smyrnensis AAD6(T)
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JOURNAL OF BIOSCIENCE AND BIOENGINEERING
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2015
2015106. Genomic analysis of Brevibacillus thermoruber 423 reveals its biotechnological and industrial potential
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APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
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2015
2015107. Triple Negative Breast Cancer: A Multi-Omics Network Discovery Strategy for Candidate Targets and Driving Pathways
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2014
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2014
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BMC SYSTEMS BIOLOGY
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2014
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2014
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2014
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2014
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2013
2013114. The Stimulatory Effect of Mannitol on Levan Biosynthesis: Lessons from Metabolic Systems Analysis of Halomonas smyrnensis AAD6(T)
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2013
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2013
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2012
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2012
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2020
20207. Drug Respositioning in Colorectal Cancer by using Co-expression Networks of P-glycoprotein
BEKLEN H., GÜLFİDAN G., ARĞA K. Y., NIELSEN J., TURANLI B.
13th The International Symposium on Health Informatics and Bioinformatics, Türkiye, 22 - 23 Ekim 2020, (Özet Bildiri)
2020
20208. DRUG REPOSITIONING IN PROSTATE CANCER THROUGH GENOME-SCALE METABOLIC MODELING
AYDOĞMUŞ E. M., gülfidan g., TURANLI B., ERZİK C., DEMİR Ü., KISAAYAK ÇOLLAK F., et al.
applied bioinformatics in life sciences, Leuven, Belçika, 13 - 14 Şubat 2020
2019
20199. Determination Of Candidate Biomarkers Through Differential Interactome in Colorectal Adenocarcinoma
BEKLEN H., GULFİDAN G., TURANLI B., ÖZBEK SARICA P., YILMAZ B., ARĞA K. Y.
The 12th International Symposium on Health Informatics and Bioinformatics (HIBIT 2019), İzmir, Türkiye, 17 - 19 Ekim 2019, (Özet Bildiri)
2019
201910. Identification of Systems Biomarkers and Candidate Drugs in Prostate Adenocarcinoma
GULFİDAN G., BEKLEN H., TURANLI B., ARĞA K. Y.
The 12th International Symposium on Health Informatics and Bioinformatics (HIBIT 2019), İzmir, Türkiye, 17 - 19 Ekim 2019, (Özet Bildiri)
2019
201911. Drug repositioning for cancer therapy by the employment of systems biology
TURANLI B., GULFİDAN G., Mardinoğlu A., ARĞA K. Y.
Cell Death: Degeneration and Regeneration Symposium, İstanbul, Türkiye, 3 - 05 Ekim 2019, (Özet Bildiri)
2019
201912. Review of the Occupational Health and Safety in the Metal Sector in Turkey
ERGİN ESEN H., ARĞA K. Y.
8. International Vocational Schools Symposium, Sinop, Türkiye, 11 - 13 Haziran 2019, (Tam Metin Bildiri)
2019
201913. Systems Biomarkers for Accurate Diagnosis, Prognosis and Therapy in Neurological Disorders
ARĞA K. Y.
FENS Regional Meeting, 10 - 13 Temmuz 2019, (Tam Metin Bildiri)
2019
201914. Understanding the metabolic reprogramming behind alkaliphilic adaptation in Bacillus marmarensis through a multi-omics data integration strategy
Altınışık F. E., Arğa K. Y., Kazan D., Sarıyar Akbulut B.
44th FEBS Congress: From molecules to living systems, Krakow, Polonya, 6 - 11 Temmuz 2019, (Özet Bildiri)
2019
201915. 112 Ambulans ve Acil Komuta Merkezi Çalışanlarında İş Sağlığı ve Güvenliği
IŞIK BARSAN Ö., ARĞA K. Y.
3rd INTERNATIONAL OCCUPATIONAL ANDENVIRONMENTAL DISEASES CONGRESS, 3 - 07 Mart 2019, (Tam Metin Bildiri)
2018
201816. Drug repositioning for the treatment of cervical cancer through host-pathogen protein-protein interactions
TURANLI B., Kori M., ARĞA K. Y.
6th International Bau Drug Design Congress, İstanbul, Türkiye, 13 - 15 Aralık 2018, (Özet Bildiri)
2018
201817. Prostat kanserinin diferansiyel protein etkileşim ağı haritasındaki yeri.
Gulfidan G., TURANLI B., ARĞA K. Y.
19. Uluslararası Katılımlı Biyoteknoloji Kongresi, Eskişehir, Türkiye, 30 Kasım - 03 Aralık 2018, (Özet Bildiri)
2018
201818. Systems Biomarkers in Cancer Diagnosis, Prognosis and Therapy
ARĞA K. Y.
2nd International Cell Death Research Congress, 1 - 04 Kasım 2018, (Özet Bildiri)
2018
201819. Prostate cancer-specific metabolic model as a tool for drug repositioning
TURANLI B., LOVRIC A., RUI B., Bidkhori G., Zhang C., ARĞA K. Y., et al.
International Conference on Applied Mathematics, Modeling and Life Sciences, 3 - 05 Ekim 2018, (Özet Bildiri)
2018
201820. Model driven discovery of drug targets for effective treatment of prostate cancer (Poster)
TURANLI B., Lovric A., Benfeitas R., Bidkhori G., Zhang C., ARĞA K. Y., et al.
Conference on Intelligent Systems for Molecular Biolog (ISMB2018), Chicago, Amerika Birleşik Devletleri, 6 - 10 Temmuz 2018, (Özet Bildiri)
2018
201821. Model driven discovery of drug targets for effective treatment of prostate cancer
TURANLI B., Benfeitas R., Lovric A., Bidkhori G., Zhang C., ARĞA K. Y., et al.
Conference on Intelligent Systems for Molecular Biolog (ISMB2018), Chicago, Amerika Birleşik Devletleri, 6 - 10 Temmuz 2018, (Özet Bildiri)
2018
201822. Comparative Analysis Of Human Cancers Through Molecular Signatures
TURANLI B., GÜLFİDAN G., ARĞA K. Y.
Applied Bioinformatics in Life Sciences, Leuven, Belçika, 8 Mart - 09 Ağustos 2018, (Özet Bildiri)
2018
201823. A metabolic network approach for the identification of drugs against prostate cancer
TURANLI B., Al Shobky M., Benfeitas R., Bidkhori G., Zhang C., ARĞA K. Y., et al.
Applied Bioinformatics in Life Sciences (2nd edition), Leuven, Belçika, 8 - 09 Mart 2018, (Özet Bildiri)
2018
201824. Kanserlerin işaretçi moleküller yoluyla karşılaştırmalı analizi
TURANLI B., Gulfidan G., ARĞA K. Y.
III.Yaşam Bilimleri Kongresi, Kayseri, Türkiye, 23 - 24 Şubat 2018, (Özet Bildiri)
2017
201725. Protein-protein interaction analysis of differentially expressed genes in head and neck cancer
İSLAM T., RAHMAN R., SHAHJAMAN M., HAQUE M. A., GÖV E., ARĞA K. Y., et al.
International Conference on Biotechnology in Health and Agriculture 2017, Dhaka, Bangladeş, 29 - 30 Aralık 2017, (Özet Bildiri)
2017
201726. Integrated analysis of transcriptome and protein interactome in colorectal cancer
RAHMAN R., İSLAM T., SHAHJAMAN M., HAQUE M. A., ARĞA K. Y., MD NURUL HAQUE M.
International Conference on Biotechnology in Health and Agriculture 2017, Dhaka, Bangladeş, 29 - 30 Aralık 2017, (Özet Bildiri)
2017
201727. Diferansiyel eş-anlatım analizi ile kansere yönelik teşhis ve tedavi amaçlı sistem biyobelirteçlerinin tayini
ERDÖL M. N., ARĞA K. Y.
19. Uluslararası Katılımlı Biyoteknoloji Kongresi, 1 - 03 Aralık 2017, (Özet Bildiri)
2017
201728. Biyoinformatik: Temel kavramlar ve klinik uygulamaları
ARĞA K. Y.
Klinisyenler için Moleküler Biyoloji ve Genetik Temel Kavramlar, İstanbul, Türkiye, 25 Kasım 2017, (Tam Metin Bildiri)
2017
201729. Transkriptom: Temel kavramlar ve klinik uygulamaları
ARĞA K. Y.
Klinisyenler için Moleküler Biyoloji ve Genetik Temel Kavramlar Sempozyumu, İstanbul, Türkiye, 25 Kasım 2017, (Tam Metin Bildiri)
2017
201730. Comprehensive mapping of differential protein interactome in human cancers
GÜLFİDAN G., TURANLI B., ARĞA K. Y.
Uluslararası Katılımlı XV. Tıbbi Biyoloji ve Genetik Kongresi, 26 - 29 Ekim 2017, (Özet Bildiri)
2017
201731. Transcriptome based systems biomarkers: a novel prognostic gene module in ovarian cancer
ARĞA K. Y., GÖV E.
Uluslararası Katılımlı XV. Tıbbi Biyoloji ve Genetik Kongresi, 26 - 29 Ekim 2017, (Özet Bildiri)
2017
201732. Using Systems Based Models to Uncover the Disease Network of Psoriasis and its associations with other autoimmune-related diseases
SEVİMOĞLU T., ARĞA K. Y., KARADAĞ A. S.
26th European Academy of Dermatology and Venereology Congress, 13 - 17 Eylül 2017, (Özet Bildiri)
2017
201733. Tissue specific reporter biomolecules in ovarian cancer: novel biomarkers and candidate therapeutic targets
GÖV E., KORİ M., ARĞA K. Y.
Sanko Üniversitesi Tıpta İnovasyon Buluşmaları-3, 11 - 13 Mayıs 2017, (Özet Bildiri)
2017
201734. Drug target identification through context-specific protein interaction networks with minimum uncertainty
ÇALIŞKAN A., AYYILDIZ D., GÖV E., ARĞA K. Y.
Sanko Üniversitesi Tıpta İnovasyon Buluşmaları-3, 11 - 13 Mayıs 2017, (Özet Bildiri)
2017
201735. Gene Expression Oriented Drug Repositoning Targets For Prostate Cancer
TURANLI B., GÜLFİDAN G., ARĞA K. Y.
Sanko Üniversitesi Tıpta İnovasyon Buluşmaları-3, 11 - 13 Mayıs 2017, (Özet Bildiri)
2017
201736. A novel in silico methodology for drug target identification based on differential interactome
GÜLFİDAN G., TURANLI B., ARĞA K. Y.
Sanko Üniversitesi Tıpta İnovasyon Buluşmaları-3, 11 - 13 Mayıs 2017, (Özet Bildiri)
2017
201737. Pea3 transkripsiyon faktörünün nöronlardaki fonksiyonuyla ilişkili yeni hedeflerin belirlenmesi
KANDEMİR B., ARĞA K. Y., YILMAZ B., KURNAZ I.
15. Ulusal sinirbilim kongresi- Uluslararası Katılımlı, 7 - 10 Mayıs 2017, (Özet Bildiri)
2017
201738. The High Potential of Network Entropy Based Differential Protein Interactome Analysis for Diagnostics Innovation in Oncology and Tumor Pathogenesis: A Case Study on Ovarian Cancer
GÖV E., AYYILDIZ D., ARĞA K. Y.
International DNA Day And Genome Congress, 24 - 28 Nisan 2017, (Özet Bildiri)
2017
201739. Genexpharma: Search Tool For Gene Expression Oriented Drug Repositoning
TURANLI B., GÜLFİDAN G., ARĞA K. Y.
International DNA Day And Genome Congress, 24 - 28 Nisan 2017, (Özet Bildiri)
2016
201640. Differential coexpression network in ovarian cancer Prognostic and therapeutic targets
GÖV E., ARĞA K. Y.
6. Multidisipliner Kanser Araştırma Kongresi, 27 - 30 Ekim 2016, (Özet Bildiri)
2016
201641. Computational anti cancer agent repurposing for pancreatic cancer
ÇALIMLIOĞLU B., GÜLFİDAN G., ÖZTÜRK R., NALBANT Z., ARĞA K. Y.
6. Multidisipliner Kanser Araştırma Kongresi, 27 - 30 Ekim 2016, (Özet Bildiri)
2016
201642. Roemerine limits carbohydrate uptake which leads to alternative nutrients such as acetyl coA sources
AYYILDIZ D., AVCI F. G., ARĞA K. Y., SARIYAR AKBULUT B.
FEBS 2016 Congress, 3 - 08 Eylül 2016, (Özet Bildiri)
2016
201643. Drug repositioning strategies aplied on a group of cancer
ÇALIMLIOĞLU B., GÜLFİDAN G., ÖZTÜRK R., NALBANT Z., ARĞA K. Y.
41. FEBS CONGRESS, 3 - 08 Eylül 2016, (Özet Bildiri)
2016
201644. A glance at smoking effect on preeclamptic placenta with transcriptional regulation approach
Aydin B., Arga K. Y.
41st FEBS Congress on Molecular and Systems Biology for a Better Life, Kusadasi, Türkiye, 3 - 08 Eylül 2016, cilt.283, ss.77, (Özet Bildiri)
2016
201645. Drug repositioning strategies applied on a group of cancer
Calimlioglu B., Ozturk R., Nalbant Z., Gulfidan G., Arga K. Y.
41st FEBS Congress on Molecular and Systems Biology for a Better Life, Kusadasi, Türkiye, 3 - 08 Eylül 2016, cilt.283, ss.140, (Özet Bildiri)
2016
201646. (-)-Roemerine limits carbohydrate uptake which leads to alternative nutrients as acetyl-CoA sources
Ayyildiz D., Avci F. G., Arga K. Y., Akbulut B. S.
41st FEBS Congress on Molecular and Systems Biology for a Better Life, Kusadasi, Türkiye, 3 - 08 Eylül 2016, cilt.283, ss.121-122, (Özet Bildiri)
2016
201647. Resemblance of human cancer stem cells based on genome-wide expression profiles
Gov E., Kaya N., Arga K. Y.
41st FEBS Congress on Molecular and Systems Biology for a Better Life, Kusadasi, Türkiye, 3 - 08 Eylül 2016, cilt.283, ss.300, (Özet Bildiri)
2016
201648. Investigating the toxic effects of nonylphenol on Saccharomyces cerevisiae
BEREKETOĞLU C., ARĞA K. Y., MERTOĞLU B.
17th European Congress on Biotechnology, 3 - 06 Temmuz 2016, (Özet Bildiri)
2016
201649. Investigating the toxic effects of nonylphenol on Saccharomyces cerevisae
BEREKETOĞLU C., ARĞA K. Y., MERTOĞLU B.
17th European Congress on Biotechnology, 3 - 06 Temmuz 2016
2016
201650. Systems biology perspective on diabetic nephropathy may reveal molecular mechanism of diabetic retinopathy
ÇALIMLIOĞLU B., ÖZTÜRK R., ARĞA K. Y.
ECB2016 17. European Congress on Biotechnology, 3 - 06 Temmuz 2016, (Özet Bildiri)
2016
201651. Investigating the toxic effects of nonylphenol on Saccharomyces cerevisiae
BEREKETOĞLU C., ARĞA K. Y., MERTOĞLU B.
ECB2016 - 17. European Congress on Biotechnology, 3 - 06 Temmuz 2016, (Özet Bildiri)
2016
201652. Transcriptional analysis of nonylphenol on Saccharomyces cerevisiae using DNA microarray
BEREKETOĞLU C., ARĞA K. Y., eraslan s., MERTOĞLU B.
EMBO Conference "Gene transcription in yeast: From chromatin to RNA and back", 11 - 16 Haziran 2016
2016
201653. Transcriptional analysis of nonylphenol on Saccharomyces cerevisiae using DNA microarray
BEREKETOĞLU C., ARĞA K. Y., Eraslan S., MERTOĞLU B.
Gene transcription in yeast: From chromatin to RNA and back, 11 - 16 Haziran 2016, (Özet Bildiri)
2016
201654. Transcriptional analysis of nonylphenol on Saccharomyces cerevisiae using DNA microarray
BEREKETOĞLU C., ARĞA K. Y., ERASLAN S., MERTOĞLU B.
Gene transcription in yeast: From chromatin to RNA and back, 11 - 16 Haziran 2016
2016
201655. Roemerine limits carbohydrate uptake which leads to alternative nutrients as acetly CoA sources
AYYILDIZ D., AVCI F. G., ARĞA K. Y., SARIYAR AKBULUT B.
THE 41TH FEBS, 3 Eylül - 08 Haziran 2016
2016
201656. Integrant roles of microRNAs and transcription factors in ovarian cancer transcriptional regulatory network
GÖV E., ARĞA K. Y.
Innovation in Medicine Summit-2, 5 - 07 Mayıs 2016, (Özet Bildiri)
2016
201657. The plant derived alkaloid roemerin is involved in the modulation of motility in E coli
AYYILDIZ D., AVCI F. G., ARĞA K. Y., BÜDEYRİ GÖKGÖZ N., SAYAR N. A., KAZAN D., et al.
BIOPHYSICAL SOCIETY 60TH ANNUAL MEETING, 27 Şubat - 02 Mart 2016
2015
201558. Multi Omic Stratejiler Yardımıyla Endometriyozis Hastalığı için Biyobelirteç Tayini
Kori M., ÇALIMLIOĞLU B., ARĞA K. Y.
4. Ulusal Moleküler Biyoloji ve Biyoteknoloji, Türkiye, 21 - 24 Ağustos 2015, (Özet Bildiri)
2015
201559. Sistem biyotıp araştırmaları için bütünleştirilmiş biyolojik ağlar yaklaşımı
ÇALIMLIOĞLU B., ARĞA K. Y.
4. ULUSAL MOLEKÜLER BİYOLOJİ VE BİYOTEKNOLOJİ KONGRESİ, Türkiye, 21 - 24 Ağustos 2015, (Özet Bildiri)
2015
201560. Transcriptomics Reveals Association Between Psoriasis and Rheumatoid Arthritis
SEVİMOĞLU T., ARĞA K. Y.
EuroMedLab Paris2015, Paris, Fransa, 21 - 25 Haziran 2015, (Özet Bildiri)
2015
201561. Genomic and Proteomic Candidate Biomarker Investigation for Personalized Medicine
Baran B., AKBAS M., ÇALIMLIOĞLU B., ARĞA K. Y.
3rd International Gen-Arel Molecular Biology and Genetics Student Congress, 24 - 25 Nisan 2015
2015
201562. Metabolic Variability Analysis Through Human Metabolic Model
ISLER E., Yavuz U., ÇALIMLIOĞLU B., ARĞA K. Y.
3rd International Gen-Arel Molecular Biology and Genetics Student Congress, 24 - 25 Nisan 2015
2014
201463. Computational association of autoimmune diseases: a case study
Sevimoglu T., Arga K. Y.
FEBS EMBO 2014 Conference, Paris, Fransa, 30 Ağustos - 04 Eylül 2014, cilt.281, ss.109-110, (Özet Bildiri)
2014
201464. Deciphering triple negative breast cancer driven pathways via multi-omic networks
Karagoz K., Sinha R., Arga K. Y.
FEBS EMBO 2014 Conference, Paris, Fransa, 30 Ağustos - 04 Eylül 2014, cilt.281, ss.452, (Özet Bildiri)
2014
201465. Uncovering the interconnectivity between infertility-associated woman diseases
Kori M., Arga K. Y.
FEBS EMBO 2014 Conference, Paris, Fransa, 30 Ağustos - 04 Eylül 2014, cilt.281, ss.276, (Özet Bildiri)
2014
201466. Research on the action mechanisms of endocrine disrupting chemicals via system biology approach
BEREKETOĞLU C., ARĞA K. Y., MERTOĞLU B.
Advanced Lecture Course on Systems Biology, Innsbruck, Avusturya, 2 - 08 Mart 2014, (Özet Bildiri)
2013
201367. Investigation of the fructose uptake system in halophilic bacteria Halomonas smyrnensis AAD6T
Aydin B., Oner E. T., Arga K. Y.
38th Congress of the Federation-of-European-Biochemical-Societies (FEBS), Saint Peter, Guernsey Ve Alderney, 6 - 11 Temmuz 2013, cilt.280, ss.559, (Özet Bildiri)
2013
201368. Characterization of the first extremophilic levansucrase purified from halophilic bacteria Halomonas smyrnensis AAD6T
Calimlioglu B., Oner E. T., Arga K. Y.
38th Congress of the Federation-of-European-Biochemical-Societies (FEBS), Saint Peter, Guernsey Ve Alderney, 6 - 11 Temmuz 2013, cilt.280, ss.178-179, (Özet Bildiri)
2013
201369. A novel levansucrase purified from halophilic bacteria halomonas smyrnensis AAD6T
TURANLI B., ARĞA K. Y., TOKSOY ÖNER E.
10th Carbohydrate Bioengineering Meeting (CBM10), Prague, Çek Cumhuriyeti, 21 - 24 Nisan 2013, (Özet Bildiri)
2011
201170. Biosensor production for foodborn pathogen salmonella enteritidis
SÜNER S., ARĞA K. Y., SESAL N. C.
The International Congress on Bioinformatics and Biomics, 18 - 22 Mayıs 2011
2010
201071. LEVAN PRODUCTION BY Halomonas sp.
Kazak H., Ates O., Kucukasik F., ARĞA K. Y., Oner E. T.
6th International Conference on Polysaccharides-Glycoscience, Prague, Çek Cumhuriyeti, 29 Eylül - 01 Ekim 2010, ss.133-134, (Tam Metin Bildiri)
2005
200572. Integrated approach to reconstruct signal transduction networks
ARĞA K. Y., Kirdar B., Ulgen K., Nielsen J.
12th European Congress on Biotechnology (ECB 12), Copenhagen, Danimarka, 21 - 24 Ağustos 2005, cilt.118, (Özet Bildiri)
2005
200573. Structural robustness of protein interaction networks are due to modularity
ARĞA K. Y., Onsan Z., Kirdar B., Nielsen J., Ulgen K.
12th European Congress on Biotechnology (ECB 12), Copenhagen, Danimarka, 21 - 24 Ağustos 2005, cilt.118, (Özet Bildiri)
Kitaplar
2022
20221. Molecular Signatures in Acute Myeloid Leukemia: From Diagnosis to Targeted Therapy and Drug Repositioning
KELEŞOĞLU N., YILMAZ B., ARĞA K. Y.
Interdisciplinary Cancer Research, Rezaei Nima, Editör, Springer, ss.1-32, 2022
2018
20182. A comprehensive overview of signaling pathways and their crosstalk in human cancers
KORİ M., AYDIN B., ARĞA K. Y.
The Most Recent Studies in Science and Art, Arapgirlioglu H., Atik A., Elliott RL., Turgeon E, Editör, Gece Kitaplığı, ss.771-784, 2018
2018
20183. Overview and new perspectives on human transcriptional regulatory network
ÇALIŞKAN A., ARĞA K. Y.
The Most Recent Studies in Science and Art, Arapgirlioglu H., Atik A., Elliott RL., Turgeon E., Editör, Gece Kitaplığı, ss.733-740, 2018
2017
20174. Systems Biomedicine: From genome scale molecular networks to efficacious biomarkers and therapeutic targets
TURANLI B., GÜLFİDAN G., ARĞA K. Y.
Researches on Science and Art in 21st Century Turkey, Hasan Arapgirlioğlu Atilla Atık Robert L. Elliot Edward Turgeon, Editör, Gece Kitaplığı, Ankara, ss.2380-2388, 2017
2016
20165. Proteins from Halophilic Bacteria: Purification and Their Applications
Turanlı B., Arğa K. Y.
Protein Purification - Principles and Trends, -, Editör, iConcept Press, Victoria-City, ss.1-23, 2016
Desteklenen Projeler
2025 - 2027
2025 - 2027Piretroid İnsektisitlerin Zebra Balığı Üzerindeki Nörotoksik ve Moleküler Etkilerinin Araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
Bereketoğlu C. (Yürütücü), Arga K. Y.
2025 - 2027
2025 - 2027Antimikrobiyal direnç gösteren klinik Pseudomonas aeruginosa izolatlarında transkriptom profilleme ile dirençli bakterileri hedefleyen yeni ilaç adaylarının keşfi ve ilaç etkinliğinin in vitro doğrulanması
TÜSEB B Grubu AR-GE Projesi
Kula C. (Yürütücü), Aksu M. B., Arga K. Y.
2023 - 2025
2023 - 2025BehçetHastalığı SeyrindeGörülen KlinikHeterojenite ve Fenotipik Farklılıklara Yol Açan Adaptif ile Doğal Bağışıklık veİnflamazom Yanıtındaki Farkların İmmunolojik Açıdan İncelenmesi
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
Erzik C., Gülfidan G., Direskeneli R. H., Deniz R., Alibaz Öner F., Bes C., et al.
2021 - 2023
2021 - 2023
Abdominal aort anevrizmasının erken teşhis ve tedavisine yönelik biyobelirteç ve ilaç adayların belirlenmesi
TÜBİTAK Projesi , 1001 - Bilimsel ve Teknolojik Araştırma Projelerini Destekleme Programı
(Proje Özeti)
Kasavi C. (Yürütücü), Arğa K. Y., Erzik C., Çalışkan M., Yılmaz B.
2018 - 2021
2018 - 2021
Integration of metabolomics and proteomics for breast cancer diagnosis
Diğer Ülkelerdeki Kamu Kurumları Tarafından Desteklenmiş Proje
Arğa K. Y., Sinha R.(Yürütücü)
2017 - 2021
2017 - 2021
Üçlü Negatif Meme Kanseri (TNMK ya da Diğer Bir Adıyla Bazal Tip) Için Prognoz ve Kemosensitivite Biyobelirteçlerin Belirlenmesi, in Vitro ve in Vivo Deneylerle Doğrulanması
TÜBİTAK Uluslararası İkili İşbirliği Projesi , 2549 - Polonya Ulusal Araştırma ve Geliştirme Merkezi (NCBR) ile İkili İşbirliği Programı
Arğa K. Y., Güre A. O.(Yürütücü)
2019 - 2020
2019 - 2020
Kolorektal kanserinde farklılaşan protein-protein etkileşimleri üzerinden ilaç repozisyonu
TÜBİTAK Projesi , 1002 - Hızlı Destek Programı
Arğa K. Y. (Yürütücü), ÖZBEK SARICA P.
2019 - 2020
2019 - 2020
Rahim ağzı kanserinin tedavisi için konakçı-patojen protein-protein etkileşimleri yoluyla ilaç repozisyonu
TÜBİTAK Projesi , 1002 - Hızlı Destek Programı
Arğa K. Y., Turanlı B.(Yürütücü)
2019 - 2020
2019 - 2020Aday biyobelirteçleri ve potansiyel terapötikleri belirlemek için kolorektal adenokarsinomda diferansiyel interaktom analizi
Yükseköğretim Kurumları Destekli Proje , BAP Y.Lisans
Arğa K. Y. (Yürütücü)
2017 - 2019
2017 - 2019
Sistem Biyolojisi Bakışı Ile Farklı Seviyelerde Biyolojik Moleküller Üzerinden Prostat Kanseri Için Ilaç Repozisyonu Uygulamaları
TÜBİTAK Projesi , 1001 - Bilimsel ve Teknolojik Araştırma Projelerini Destekleme Programı
Arğa K. Y. (Yürütücü), Kısaayak Çollak F., Erzik C., Demir Ü., Turanlı B.
2018 - 2018
2018 - 2018
Kanserde protein etkileşimlerinin dinamik haritalaması
Yükseköğretim Kurumları Destekli Proje , BAP Y.Lisans
Arğa K. Y. (Yürütücü)
2017 - 2018
2017 - 2018
Hesaplamalı Sistem Biyolojisi Yaklaşımı Ile Kanser Ilintili Işaretçi Moleküllerin Tespiti Ve Haritalanması
TÜBİTAK Projesi , 1002 - Hızlı Destek Programı
Arğa K. Y. (Yürütücü), TURANLI B.
2016 - 2018
2016 - 2018
Aday kanser karşıtı ilaçların bulunması için sistem biyotıp ve farmakolojisi yaklaşımı ile ilaç repozisyonu
Yükseköğretim Kurumları Destekli Proje , BAP Doktora
Arğa K. Y. (Yürütücü), TURANLI B.
2016 - 2017
2016 - 2017Mayada TOR sinyal iletiminde yeni yolizlerinin tespiti ve araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
Arğa K. Y. (Yürütücü)
2015 - 2017
2015 - 2017
Mezenkimal kök hücrelerin over kanser hücre hatları ile etkileşimine sistem biyolojisi yaklaşımı
Yükseköğretim Kurumları Destekli Proje , BAP Doktora
Arğa K. Y. (Yürütücü)
2015 - 2016
2015 - 2016Agresif ve agresif olmayan papiller tiroid karsinomunda miRNA ve mRNA ekspresyon profillerinin ve gen miRNA ilişkisinin belirlenip biyolojik ağlarla ilişkilendirilmesi
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
Arğa K. Y., Akyay Z.(Yürütücü)
2014 - 2016
2014 - 2016Sistem biyolojisi yaklaşımı ile Psoriazis Sedef hastalığı ile ilintili biyobelirteç tayini
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
Arğa K. Y. (Yürütücü)
2013 - 2016
2013 - 2016Endokrin bozucu bileşiklerin Saccharomyces cerevisiae genomunun transkripsiyon profilleri üzerindeki etkilerinin moleküler metotlarla araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Doktora
Arğa K. Y., Mertoğlu B. (Yürütücü)
2013 - 2016
2013 - 2016Biyoproses otomatik kontrol araştırma geliştirme ve eğitim kompleksi
Yükseköğretim Kurumları Destekli Proje , BAP Alt Yapı
Arğa K. Y., Kazan D. (Yürütücü)
2012 - 2016
2012 - 2016Yeni nesil biyoyakıt teknolojileri için ekstremofiller
TÜBİTAK Uluslararası İkili İşbirliği Projesi , 2504 - İtalya Ulusal Araştırma Konseyi (CNR) İkili İşbirliği Programı
Arğa K. Y., Toksoy Öner E. (Yürütücü)
2011 - 2015
2011 - 2015Levan bazlı polimerlerin biyolojik aktivitelerinin in vitro ve in silico incelenmesi
TÜBİTAK Projesi , 1001 - Bilimsel ve Teknolojik Araştırma Projelerini Destekleme Programı
Arğa K. Y., Toksoy Öner E. (Yürütücü)
2013 - 2014
2013 - 2014Artırılmış levan biyosentezi stratejileri tasarlamak için Halomonas smyrnensis AAD6T deki fruktoz alımının araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Y.Lisans
Arğa K. Y. (Yürütücü)
2013 - 2014
2013 - 2014Halomonas smyrnensis AAD6T den izole edilen levansukraz enziminin saflaştırılması ve karakterizasyonu
Yükseköğretim Kurumları Destekli Proje , BAP Y.Lisans
Arğa K. Y. (Yürütücü)
2012 - 2014
2012 - 2014Levan Bazlı Polimerlerin Biyolojik Aktivitelerinin In Vitro ve In Silico İncelenmesi
TÜBİTAK Projesi , 1001 - Bilimsel ve Teknolojik Araştırma Projelerini Destekleme Programı
Arğa K. Y., Toksoy Öner E. (Yürütücü)
2011 - 2014
2011 - 2014Mikrobiyal biyopolimer üretiminin sistem bazlı optimizasyonu
TÜBİTAK Projesi , 3501 - Ulusal Genç Araştırmacı Kariyer Geliştirme Programı
Arğa K. Y. (Yürütücü)
2013 - 2013
2013 - 2013Levan üreten Halomonas smyrnensis AAD6 için biyoinformatik temelli metabolik ağyapı oluşturulması
Yükseköğretim Kurumları Destekli Proje , BAP Y.Lisans
Arğa K. Y. (Yürütücü)
2011 - 2013
2011 - 2013Biyopolimer üretim mekanizmalarının metabolik ağyapılar ile aydınlatılması
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
Arğa K. Y. (Yürütücü)
2011 - 2012
2011 - 2012