A system based network approach to ethanol tolerance in Saccharomyces cerevisiae

Kasavi C. , Eraslan S., ARĞA K. Y. , Oner E. T. , KIRDAR B.

BMC SYSTEMS BIOLOGY, cilt.8, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier


Background: Saccharomyces cerevisiae has been widely used for bio-ethanol production and development of rational genetic engineering strategies leading both to the improvement of productivity and ethanol tolerance is very important for cost-effective bio-ethanol production. Studies on the identification of the genes that are up-or down-regulated in the presence of ethanol indicated that the genes may be involved to protect the cells against ethanol stress, but not necessarily required for ethanol tolerance.