A system based network approach to ethanol tolerance in Saccharomyces cerevisiae
BMC SYSTEMS BIOLOGY, cilt.8, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 8
- Basım Tarihi: 2014
- Doi Numarası: 10.1186/s12918-014-0090-6
- Dergi Adı: BMC SYSTEMS BIOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Anahtar Kelimeler: Ethanol tolerance network, Candidate genes, Saccharomyces cerevisiae, Protein-protein interaction network, CELL-GROWTH, PROTEIN, YEAST, GENE, MODULARITY, IDENTIFICATION, STRESS, FERMENTATION, FAMILY, LOCALIZATION
- Marmara Üniversitesi Adresli: Evet
Özet
Background: Saccharomyces cerevisiae has been widely used for bio-ethanol production and development of rational genetic engineering strategies leading both to the improvement of productivity and ethanol tolerance is very important for cost-effective bio-ethanol production. Studies on the identification of the genes that are up-or down-regulated in the presence of ethanol indicated that the genes may be involved to protect the cells against ethanol stress, but not necessarily required for ethanol tolerance.