Prof. Dr. AJDA ÇOKER GÜRKAN

Yayın Ağı

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

The Suppressive Effect of Novel Hydrazones-Tethered Imidazoles in HCT-116 and HT-29 Colorectal Cancer Cells: Synthesis, Biological Activity and Molecular Modeling Studies

Kekeçmuhammed H., Tapera M., Şahin K., Öztürk Sever B., Anber A. M., BORA R. E., et al.

ChemistrySelect , cilt.9, sa.19, 2024 (SCI-Expanded)

Epibrassinolide impaired colon tumor progression and induced autophagy in SCID mouse xenograft model via acting on cell cycle progression without affecting endoplasmic reticulum stress observed in vitro

YERLİKAYA P. O., Adacan K., KARATUĞ KAÇAR A., ÇOKER GÜRKAN A., Arisan E. D.

International Journal of Biochemistry and Cell Biology , cilt.155, 2023 (SCI-Expanded) Sürdürülebilir Kalkınma

The protective impact of growth hormone against rotenone-induced apoptotic cell death via acting on endoplasmic reticulum stress and autophagy axis

Berrak Rencüzoğullari Ö., Tornaci S., Çelik Y., Ciroğlu N. N., YERLİKAYA P. O., Arisan E. D., et al.

Turkish Journal of Biology , cilt.47, sa.1, ss.29-43, 2023 (SCI-Expanded) Sürdürülebilir Kalkınma

Palbociclib negatively regulates fatty acid synthesis due to upregulation of AMPK alpha and miR-33a levels to increase apoptosis in Panc-1 and MiaPaCa-2 cells

Rencuzogullari O., Yerlikaya P. O., Gurkan A., Arisan E. D., Telci D.

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY , cilt.69, sa.1, ss.342-354, 2022 (SCI-Expanded) Sürdürülebilir Kalkınma

miR27a, a fine-tuning molecule, interacts with growth hormone (GH) signaling and ornithine decarboxylase (ODC) via targeting STAT5

Coker-Gurkan A., Koyuncu K., Yerlikaya P. O., Arisan E. D.

AMINO ACIDS , cilt.54, sa.1, ss.71-84, 2022 (SCI-Expanded)

In Vitro Investigations of miR-33a Expression in Estrogen Receptor-Targeting Therapies in Breast Cancer Cells

Ozfiliz-Kilbas P., Sonmez O., Obakan-Yerlikaya P., Coker-Gurkan A., Palavan-Unsal N., Uysal-Onganer P., et al.

CANCERS , cilt.13, sa.21, 2021 (SCI-Expanded)

Epibrassinolide prevents tau hyperphosphorylation via GSK3 beta inhibition in vitro and improves Caenorhabditis elegans lifespan and motor deficits in combination with roscovitine

Yerlikaya P. O., Arisan E. D., Gurkan A., Okumus O. O., Yenigun T., Ozbey U., et al.

AMINO ACIDS , cilt.53, sa.9, ss.1373-1389, 2021 (SCI-Expanded) Sürdürülebilir Kalkınma

Atiprimod triggered apoptotic cell death via acting on PERK/eIF2 alpha/ATF4/CHOP and STAT3/NF-Kappa B axis in MDA-MB-231 and MDA-MB-468 breast cancer cells

Coker-Gurkan A., Can E., Sahin S., Obakan-Yerlikaya P., Arisan E.

MOLECULAR BIOLOGY REPORTS , cilt.48, sa.6, ss.5233-5247, 2021 (SCI-Expanded)

Proinflammatory cytokine profile is critical in autocrine GH-triggered curcumin resistance engulf by atiprimod cotreatment in MCF-7 and MDA-MB-231 breast cancer cells

Coker-Gurkan A., Ozakaltun B., Akdeniz B., Ergen B., Obakan-Yerlikaya P., AKKOÇ T., et al.

MOLECULAR BIOLOGY REPORTS , cilt.47, sa.11, ss.8797-8808, 2020 (SCI-Expanded) Sürdürülebilir Kalkınma

Specific c-Jun N-Terminal Kinase Inhibitor, JNK-IN-8 Suppresses Mesenchymal Profile of PTX-Resistant MCF-7 Cells through Modulating PI3K/Akt, MAPK and Wnt Signaling Pathways

Ozfiliz Kilbas P., Sonmez O., Uysal-Onganer P., Coker Gurkan A., Obakan Yerlikaya P., Arisan E. D.

BIOLOGY-BASEL , cilt.9, sa.10, 2020 (SCI-Expanded)

The role of the PI3K/AKT/mTOR signaling axis in the decision of the celastrol-induced cell death mechanism related to the lipid regulatory pathway in prostate cancer cells

Arisan E. D., Rencuzogullari O., Coban M., Sevgin B., Obakan-Yerlikaya P., Coker-Gurkan A., et al.

PHYTOCHEMISTRY LETTERS , cilt.39, ss.73-83, 2020 (SCI-Expanded) Sürdürülebilir Kalkınma

Epibrassinolide-induced autophagy occurs in an Atg5-independent manner due to endoplasmic stress induction in MEF cells

Adacan K., Obakan-Yerlikaya P., Arisan E. D., Coker-Gurkan A., Kaya R. I., Palavan-Unsal N.

AMINO ACIDS , cilt.52, sa.6-7, ss.871-891, 2020 (SCI-Expanded) Sürdürülebilir Kalkınma

Palbociclib, a selective CDK4/6 inhibitor, restricts cell survival and epithelial-mesenchymal transition in Panc-1 and MiaPaCa-2 pancreatic cancer cells

Rencuzogullari O., Yerlikaya P. O., Gurkan A., Arisan E. D., Telci D.

JOURNAL OF CELLULAR BIOCHEMISTRY , cilt.121, sa.1, ss.508-523, 2020 (SCI-Expanded) Sürdürülebilir Kalkınma

The molecular targets of diclofenac differs from ibuprofen to induce apoptosis and epithelial mesenchymal transition due to alternation on oxidative stress management p53 independently in PC3 prostate cancer cells

Arisan E. D., Akar R. O., Rencuzogullari O., Yerlikaya P. O., Gurkan A., Akin B., et al.

PROSTATE INTERNATIONAL , cilt.7, sa.4, ss.156-165, 2019 (SCI-Expanded) Sürdürülebilir Kalkınma

Atiprimod induce apoptosis in pituitary adenoma: Endoplasmic reticulum stress and autophagy pathways

Coker-Gurkan A., Ayhan-Sahin B., Keceloglu G., Obakan-Yerlikaya P., Arisan E., Palavan-Unsal N.

JOURNAL OF CELLULAR BIOCHEMISTRY , cilt.120, sa.12, ss.19749-19763, 2019 (SCI-Expanded)

Inhibition of extracellular signal-regulated kinase potentiates the apoptotic and antimetastatic effects of cyclin-dependent kinase inhibitors on metastatic DU145 and PC3 prostate cancer cells

Rencuzogullari O., Arisan E. D., Yerlikaya P. O., Gurkan A., Keskin B., Unsal N. P.

JOURNAL OF CELLULAR BIOCHEMISTRY , cilt.120, sa.4, ss.5558-5569, 2019 (SCI-Expanded) Sürdürülebilir Kalkınma

Curcumin prevented human autocrine growth hormone (GH) signaling mediated NF-kappa B activation and miR-183-96-182 cluster stimulated epithelial mesenchymal transition in T47D breast cancer cells

Coker-Gurkan A., Bulut D., Genc R., Arisan E., Obakan-Yerlikaya P., Palavan-Unsal N.

MOLECULAR BIOLOGY REPORTS , cilt.46, sa.1, ss.355-369, 2019 (SCI-Expanded) Sürdürülebilir Kalkınma

Diclofenac induced apoptosis via altering PI3K/Akt/MAPK signaling axis in HCT 116 more efficiently compared to SW480 colon cancer cells

Arisan E. D., Ergul Z., Bozdag G., Rencuzogullari O., Coker-Gurkan A., Obakan-Yerlikaya P., et al.

MOLECULAR BIOLOGY REPORTS , cilt.45, sa.6, ss.2175-2184, 2018 (SCI-Expanded) Sürdürülebilir Kalkınma

Cyclin-dependent kinase inhibitors, roscovitine and purvalanol, induce apoptosis and autophagy related to unfolded protein response in HeLa cervical cancer cells

Ozfiliz-Kilbas P., Sarikaya B., Obakan-Yerlikaya P., Coker-Gurkan A., Arisan E. D., Temizci B., et al.

MOLECULAR BIOLOGY REPORTS , cilt.45, sa.5, ss.815-828, 2018 (SCI-Expanded) Sürdürülebilir Kalkınma

Curcumin inhibits autocrine growth hormone-mediated invasion and metastasis by targeting NF-kappa B signaling and polyamine metabolism in breast cancer cells

Coker-Gurkan A., Celik M., Ugur M., Arisan E., Obakan-Yerlikaya P., Durdu Z. B., et al.

AMINO ACIDS , cilt.50, sa.8, ss.1045-1069, 2018 (SCI-Expanded) Sürdürülebilir Kalkınma

Inhibition of autophagy enhances DENSpm-induced apoptosis in human colon cancer cells in a p53 independent manner

Gurkan A., Arisan E. D., Yerlikaya P. O., Ilhan H., Unsal N. P.

CELLULAR ONCOLOGY , cilt.41, sa.3, ss.297-317, 2018 (SCI-Expanded) Sürdürülebilir Kalkınma

Calreticulin is a fine tuning molecule in epibrassinolide-induced apoptosis through activating endoplasmic reticulum stress in colon cancer cells

Obakan-Yerlikaya P., Arisan E. D., Coker-Gurkan A., Adacan K., Ozbey U., Somuncu B., et al.

MOLECULAR CARCINOGENESIS , cilt.56, sa.6, ss.1603-1619, 2017 (SCI-Expanded) Sürdürülebilir Kalkınma

DENSpm overcame Bcl-2 mediated resistance against Paclitaxel treatment in MCF-7 breast cancer cells via activating polyamine catabolic machinery

Akyol Z., Coker-Gurkan A., Arisan E. D., Obakan-Yerlikaya P., Palavan-Unsal N.

BIOMEDICINE & PHARMACOTHERAPY , cilt.84, ss.2029-2041, 2016 (SCI-Expanded) Sürdürülebilir Kalkınma

mTOR is a fine tuning molecule in CDK inhibitors-induced distinct cell death mechanisms via PI3K/AKT/mTOR signaling axis in prostate cancer cells

Berrak O., Arisan E. D., Obakan-Yerlikaya P., Coker-Gurkan A., Palavan-Unsal N.

APOPTOSIS , cilt.21, sa.10, ss.1158-1178, 2016 (SCI-Expanded) Sürdürülebilir Kalkınma

The inhibition of PI3K and NF kappa B promoted curcumin-induced cell cycle arrest at G2/M via altering polyamine metabolism in Bcl-2 overexpressing MCF-7 breast cancer cells

Berrak O., Akkoc Y., Arisan E. D., Coker-Gurkan A., Obakan-Yerlikaya P., Palavan-Unsal N.

BIOMEDICINE & PHARMACOTHERAPY , cilt.77, ss.150-160, 2016 (SCI-Expanded) Sürdürülebilir Kalkınma

Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells

Coskun D., Obakan P., Arisan E. D., Coker-Gurkan A., Palavan-Unsal N.

EXPERIMENTAL CELL RESEARCH , cilt.338, sa.1, ss.10-21, 2015 (SCI-Expanded) Sürdürülebilir Kalkınma

SILAC-Based Mass Spectrometry Analysis Reveals That Epibrassinolide Induces Apoptosis via Activating Endoplasmic Reticulum Stress in Prostate Cancer Cells

Obakan P., Barrero C., Coker-Gurkan A., Arisan E. D., Merali S., Palavan-Unsal N.

PLOS ONE , cilt.10, sa.9, 2015 (SCI-Expanded) Sürdürülebilir Kalkınma

Fetuin-A 742 (C/T) and 766 (C/G) polymorphic sites are associated with increased risk of myocardial infarction in older patients (40 years of age)

Coker-Gurkan A., Coskun D., Arisan E. D., Obakan P., Soylu O., Unsal N. P.

MOLECULAR MEDICINE REPORTS , cilt.12, sa.1, ss.1356-1362, 2015 (SCI-Expanded)

Purvalanol induces endoplasmic reticulum stress-mediated apoptosis and autophagy in a time-dependent manner in HCT116 colon cancer cells

Coker-Gurkan A., Arisan E. D., Obakan P., Akalln K., Ozbey U., Palavan-Unsal N.

ONCOLOGY REPORTS , cilt.33, sa.6, ss.2761-2770, 2015 (SCI-Expanded)

Polyamines modulate the roscovitine-induced cell death switch decision autophagy vs. apoptosis in MCF-7 and MDA-MB-231 breast cancer cells

Arisan E. D., Akkoc Y., Akyuz K. G., Kerman E. M., Obakan P., Coker-Gurkan A., et al.

MOLECULAR MEDICINE REPORTS , cilt.11, sa.6, ss.4532-4540, 2015 (SCI-Expanded)

Inhibition of PI3K signaling triggered apoptotic potential of curcumin which is hindered by Bcl-2 through activation of autophagy in MCF-7 cells

Akkoc Y., Berrak O., Arisan E. D., Obakan P., Coker-Gurkan A., Palavan-Unsal N.

BIOMEDICINE & PHARMACOTHERAPY , cilt.71, ss.161-171, 2015 (SCI-Expanded) Sürdürülebilir Kalkınma

Roscovitine-treated He La cells finalize autophagy later than apoptosis by downregulating Bcl-2

Coker-Gurkan A., Arisan E. D., Obakan P., Ozfiliz P., Kose B., Bickici G., et al.

MOLECULAR MEDICINE REPORTS , cilt.11, sa.3, ss.1968-1974, 2015 (SCI-Expanded)

Lack of functional p53 renders DENSpm-induced autophagy and apoptosis in time dependent manner in colon cancer cells

Coker-Gurkan A., Arisan E. D., Obakan P., Palavan-Unsal N.

AMINO ACIDS , cilt.47, sa.1, ss.87-100, 2015 (SCI-Expanded) Sürdürülebilir Kalkınma

Epibrassinolide-induced apoptosis regardless of p53 expression via activating polyamine catabolic machinery, a common target for androgen sensitive and insensitive prostate cancer cells

Obakan P., Arisan E. D., Coker-Gurkan A., Palavan-Unsal N.

PROSTATE , cilt.74, sa.16, ss.1622-1633, 2014 (SCI-Expanded) Sürdürülebilir Kalkınma

Inhibition of autophagy by 3-MA potentiates purvalanol-induced apoptosis in Bax deficient HCT 116 colon cancer cells

Coker-Gurkan A., Arisan E. D., Obakan P., Guvenir E., Unsal N. P.

EXPERIMENTAL CELL RESEARCH , cilt.328, sa.1, ss.87-98, 2014 (SCI-Expanded) Sürdürülebilir Kalkınma

Cathepsin K analysis in a pycnodysostosis cohort: demographic, genotypic and phenotypic features

Arman A., Bereket A., Çoker A., Şimşek Kiper P. Ö., Güran T., Özkan B., et al.

ORPHANET JOURNAL OF RARE DISEASES , cilt.9, 2014 (SCI-Expanded)

Purvalanol A is a strong apoptotic inducer via activating polyamine catabolic pathway in MCF-7 estrogen receptor positive breast cancer cells

Obakan P., Arisan E. D., Ozfiliz P., Coker-Gurkan A., Palavan-Unsal N.

MOLECULAR BIOLOGY REPORTS , cilt.41, sa.1, ss.145-154, 2014 (SCI-Expanded) Sürdürülebilir Kalkınma

CDK Inhibitors Induce Mitochondria-mediated Apoptosis Through the Activation of Polyamine Catabolic Pathway in LNCaP, DU145 and PC3 Prostate Cancer Cells

Arisan E. D., Obakan P., Coker-Gurkan A., Calcabrini A., Agostinelli E., Unsal N. P.

CURRENT PHARMACEUTICAL DESIGN , cilt.20, sa.2, ss.180-188, 2014 (SCI-Expanded) Sürdürülebilir Kalkınma

Bag-1L is a Stress-withstand Molecule Prevents the Downregulation of Mcl-1 and c-Raf Under Control of Heat Shock Proteins in Cisplatin Treated HeLa Cervix Cancer Cells

Ozfiliz P., Arisan E. D., Coker-Gurkan A., Obakan P., Eralp T. N., Dinler-Doganay G., et al.

ASIAN PACIFIC JOURNAL OF CANCER PREVENTION , cilt.15, sa.11, ss.4475-4482, 2014 (SCI-Expanded)

Downregulation of c-Myc mediated ODC expression after purvalanol treatment is under control of upstream MAPK signaling axis in MCF-7 breast cancer cells

Obakan P., Alkurt G., Kose B., Gurkan A., Arisan E. D., Coskun D., et al.

TURKISH JOURNAL OF BIOLOGY , cilt.38, sa.6, ss.867-879, 2014 (SCI-Expanded)

Assessment of Interleukin-1 Gene Cluster Polymorphisms in Lone Atrial Fibrillation: New Insight into the Role of Inflammation in Atrial Fibrillation

Gungor B., Ekmekci A., ARMAN A., Ozcan K. S., Ucer E., Alper A. T., et al.

PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY , cilt.36, sa.10, ss.1220-1227, 2013 (SCI-Expanded)

Multiple sclerosis: association with the interleukin-1 gene family polymorphisms in the Turkish population

Isik N., ARMAN A., Canturk I. A., Gurkan A., Candan F., Aktan S., et al.

INTERNATIONAL JOURNAL OF NEUROSCIENCE , cilt.123, sa.10, ss.711-718, 2013 (SCI-Expanded)

Lack of association between IL-6 gene polymorphisms and rheumatoid arthritis in Turkish population

Arman A., Coker A., Sarioz O., Inanc N., Direskeneli H.

RHEUMATOLOGY INTERNATIONAL , cilt.32, sa.7, ss.2199-2201, 2012 (SCI-Expanded)

Inhibition of ornithine decarboxylase alters the roscovitine-induced mitochondrial-mediated apoptosis in MCF-7 breast cancer cells

Arisan E. D., Obakan P., Coker A., Palavan-Unsal N.

MOLECULAR MEDICINE REPORTS , cilt.5, sa.5, ss.1323-1329, 2012 (SCI-Expanded)

Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells

Coker A., Arisan E. D., Palavan-Unsal N.

MOLECULAR MEDICINE REPORTS , cilt.5, sa.4, ss.1037-1042, 2012 (SCI-Expanded)

Polyamine depletion enhances the roscovitine-induced apoptosis through the activation of mitochondria in HCT116 colon carcinoma cells

Arisan E. D., Coker A., Palavan-Unsal N.

AMINO ACIDS , cilt.42, sa.2-3, ss.655-665, 2012 (SCI-Expanded) Sürdürülebilir Kalkınma

Lack of association between IL-1 and IL-6 gene polymorphisms and myocardial infarction in Turkish population

Coker A., Arman A., Soylu O., Tezel T., Yildirim A.

INTERNATIONAL JOURNAL OF IMMUNOGENETICS , cilt.38, sa.3, ss.201-208, 2011 (SCI-Expanded) Sürdürülebilir Kalkınma

Raman micro-spectroscopic investigation of the interaction of cultured HCT116 colon cancer cells with alpha-difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase

Akyuz S., ÖZEL A., BALCI K., Akyuz T., Coker A., Arisan E. D., et al.

JOURNAL OF MOLECULAR STRUCTURE , cilt.993, sa.1-3, ss.319-323, 2011 (SCI-Expanded) Sürdürülebilir Kalkınma

Raman micro-spectroscopic analysis of cultured HCT116 colon cancer cells in the presence of roscovitine

Akyuz S., ÖZEL A., BALCI K., Akyuz T., Coker A., Arisan E. D., et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY , cilt.78, sa.5, ss.1540-1547, 2011 (SCI-Expanded) Sürdürülebilir Kalkınma

Novel Growth Hormone Receptor Gene Mutation in a Patient with Laron Syndrome

ARMAN A., YÜKSEL B., ÇOKER A., Sarioz O., Temiz F., TOPALOĞLU A. K.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM , cilt.23, sa.4, ss.407-414, 2010 (SCI-Expanded)

Characterization of GH-1 Mutations in Children with Isolated Growth Hormone Deficiency in the Turkish Population

Coker A., Cetinkaya E., Dundar B., Siklar Z., Buyukgebiz A., Arman A.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM , cilt.22, sa.10, ss.937-946, 2009 (SCI-Expanded)

Interleukin-1 Receptor Antagonist Gene VNTR Polymorphism is Associated with Coronary Artery Disease

Arman A., Soylu O., Yildirim A., Furman A., Ercelen N., Aydogan H., et al.

ARQUIVOS BRASILEIROS DE CARDIOLOGIA , cilt.91, sa.5, ss.268-273, 2008 (SCI-Expanded)

Interleukin-1B (-511) gene polymorphism is associated with acute coronary syndrome in the Turkish population

Soylu O., Yildirim A., Coker A., Tezel T., List E. O., ARMAN A.

EUROPEAN CYTOKINE NETWORK , cilt.19, sa.1, ss.42-48, 2008 (SCI-Expanded) Sürdürülebilir Kalkınma

Novel splice site mutation in the growth hormone receptor gene in Turkish patients with Laron-type dwarfism

ARMAN A., Ozon A., Isguven P. S., Coker A., PEKER İ., Yordam N.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM , cilt.21, sa.1, ss.47-58, 2008 (SCI-Expanded)

Interleukin-1 receptor antagonist (IL-1RN) and interleukin-1B gene polymorphisms in Turkish patients with rheumatoid arthritis

Arman A., Yilmaz B., Coker A., Inanc N., Direskeneli H.

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY , cilt.24, sa.6, ss.643-648, 2006 (SCI-Expanded)

Diğer Dergilerde Yayınlanan Makaleler

Lack of evidence for the association of ornithine decarboxylase (+ 316 G> A), spermidine/spermine acetyl transferase (-1415 T> C) gene polymorphisms with calcium oxalate stone disease

Coker-Gurkan A., Arisan S., Arisan E. D., Unsal N. P.

BIOMEDICAL REPORTS , cilt.2, sa.1, ss.69-74, 2014 (ESCI)

Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar

The identification of protein expression profile of PC3 prostate cancer and PNTIA prostate epithelial cells following anti-obesity drug Orlistat treatment regardless of AMPK signaling

ÖZFİLİZ KILBAŞ P., NEBİLER E., ARISAN E. D., ÇOKER GÜRKAN A., OBAKAN YERLİKAYA P., ÜNSAL Z. N.

6th International BAU Drug Design Congress, İstanbul, Türkiye, 13 - 15 Aralık 2018, ss.120 Sürdürülebilir Kalkınma

Metrikler

Yayın

Atıf (WoS)

593

H-İndeks (WoS)

Atıf (Scopus)

631

H-İndeks (Scopus)

Atıf (Scholar)

H-İndeks (Scholar)

Proje

Tez Danışmanlığı

Açık Erişim

BM Sürdürülebilir Kalkınma Amaçları

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