Interleukin-1 receptor antagonist (IL-1RN) and interleukin-1B gene polymorphisms in Turkish patients with rheumatoid arthritis
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, cilt.24, sa.6, ss.643-648, 2006 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 24 Sayı: 6
- Basım Tarihi: 2006
- Dergi Adı: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.643-648
- Anahtar Kelimeler: 1L-1B and IL-1RN polymorphism, rheumatoid arthritis, SYSTEMIC-LUPUS-ERYTHEMATOSUS, DISEASE-ACTIVITY, TANDEM REPEAT, PLASMA-LEVELS, ASSOCIATION, POPULATION, IL-1-BETA, SECRETION, SEVERITY, TURKEY
- Marmara Üniversitesi Adresli: Evet
Özet
Objective Interleukin I (IL-1) family is composed of two agonists, IL-1 alpha and IL-1 beta and IL-1 receptor antagonist, IL-1Ra. The purpose of this study was to determine the relationship between polymorphisms of IL-1 receptor antagonist (IL-1RN), IL-1B promoter and IL-1B exon 5 genes and susceptibility to rheumatoid arthritis (RA) in Turkish population.