Assessment of Interleukin-1 Gene Cluster Polymorphisms in Lone Atrial Fibrillation: New Insight into the Role of Inflammation in Atrial Fibrillation


Gungor B., Ekmekci A., ARMAN A. , Ozcan K. S. , Ucer E., Alper A. T. , ...Daha Fazla

PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, cilt.36, ss.1220-1227, 2013 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 36 Konu: 10
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1111/pace.12182
  • Dergi Adı: PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
  • Sayfa Sayıları: ss.1220-1227

Özet

BackgroundSystemic inflammation is accepted as one of the pathophysiological mechanisms of atrial fibrillation (AF). The role of inflammation has been shown previously. Interleukin (IL) system is the main modulator of the inflammatory responses and genetic polymorphisms of IL-1 cluster genes are associated with increased risk for inflammatory diseases.