Publication Network
Education Information
2011 - 2017
2011 - 2017Doctorate
Marmara University, Faculty Of Pharmacy, Professional Pharmaceutical Sciences, Turkey
2007 - 2010
2007 - 2010Postgraduate
Marmara University, Faculty Of Pharmacy, Professional Pharmaceutical Sciences, Turkey
2003 - 2007
2003 - 2007Undergraduate
Marmara University, Faculty Of Arts And Sciences, Chemistry, Turkey
Dissertations
2017
2017Doctorate
Olası antiviral/antibakteriyel etkili 2-imino/ tiyokso-4-tiyazolidinon türevlerinin sentezi
Marmara Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
2010
2010Postgraduate
Olası antiviral etkili 4h-1,2,4-triazol-3-tiyoasetamit türevlerinin sentezi
Marmara Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
Foreign Languages
B1 Intermediate
B1 IntermediateEnglish
Certificates, Courses and Trainings
2018
2018AGILENT 1260 INFINITY II LC DAD HARDWARE and OPENLAB CHEMSTATION SOFTWARE
Health&Medicine
Sem Laboratuvar Cihazları
2014
2014In Siliko Teknikler-1: Üç Boyutlu Protein Yapı Tahmini Modelleme ve Simülasyonları, Bilgisayar Destekli İlaç Tasarımı ile İlaç-Reseptör Etkileşimlerinin In Siliko Teknikler Kullanılarak Aydınlatılması
Health&Medicine
Bahçeşehir Üniversitesi
2013
2013Computer-Aided Drug Design Workshop, COMPUTER-AIDED DRUG DISCOVERY AND DEVELOPMENT (CADDD): in silico-chemico-biological approach
Health&Medicine
Bahçeşehir Üniversitesi
2013
2013İlaç Araştırmalarında Uygulamalı Moleküler Modelleme ve Simülasyon Teknikleri, Bilgisayar Ortamında Yapı-Aktivite ilişkileri, Moleküler Kenetlenme, Farmakofor Çalışmaları ile Olası Etkileşimlerin Aydınlatılması
Health&Medicine
Hacettepe Üniversitesi
Research Areas
Pharmacology and Therapeutics, Professional Sciences
Academic Titles / Tasks
2018 - Continues
2018 - ContinuesAssistant Professor
Marmara University, Faculty Of Pharmacy, Professional Pharmaceutical Sciences
2012 - 2018
2012 - 2018Research Assistant
Marmara University, Faculty Of Pharmacy, Professional Pharmaceutical Sciences
Managerial Experience
2013 - 2014
2013 - 2014Fakülte Araştırma Görevlisi Temsilciliği
Marmara University, Faculty of Pharmacy, Professional Pharmaceutical Sciences
Courses
Articles Published in Journals That Entered SCI, SSCI and AHCI Indexes
2022
2022Novel fluoroquinolones containing 2-arylamino-2-oxoethyl fragment: Design, synthesis, evaluation of antibacterial and antituberculosis activities and molecular modeling studies
KULABAŞ N. , TÜRE A. , Bozdeveci A., Krishna V. S. , ALPAY KARAOĞLU Ş., Sriram D., et al.
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2022 (Journal Indexed in SCI)
2021
2021Synthesis and structure-activity relationship of L-methionine-coupled 1,3,4-thiadiazole derivatives with activity against influenza virus
TATAR E. , Yaldiz S., KULABAŞ N. , Vanderlinden E., Naesens L., KÜÇÜKGÜZEL İ.
CHEMICAL BIOLOGY & DRUG DESIGN, 2021 (Journal Indexed in SCI)
2020
2020Synthesis, molecular docking and evaluation of novel sulfonyl hydrazones as anticancer agents and COX-2 inhibitors
Şenkardeş S. , Han M. İ. , Kulabaş N. , Abbak M., Çevik Ö., Küçükgüzel İ. , et al.
Molecular Diversity, vol.24, no.3, pp.673-689, 2020 (Journal Indexed in SCI)
2019
2019Design, synthesis and molecular modeling studies on novel moxifloxacin derivatives as potential antibacterial and antituberculosis agents
TÜRE A. , KULABAŞ N. , Dingiş S. İ. , Birgül K., Bozdeveci A., ALPAY KARAOĞLU Ş., et al.
Bioorganic Chemistry, vol.88, 2019 (Journal Indexed in SCI)
2018
2018One-pot, Four-Component Green Synthesis, Carbonic Anhydrase II Inhibition and Docking Studies of 5-Arylidenerhodanines
Mermer A., DEMİRBAŞ N., ÇOLAK A., Demir E. A. , KULABAŞ N. , DEMİRBAŞ A.
CHEMISTRYSELECT, vol.3, no.43, pp.12234-12242, 2018 (Journal Indexed in SCI)
2016
2016Synthesis and antiproliferative evaluation of novel 2-(4H-1,2,4-triazole-3-ylthio)acetamide derivatives as inducers of apoptosis in cancer cells
KULABAŞ N. , TATAR E. , BİNGÖL ÖZAKPINAR Ö. , ÖZSAVCI D. , Pannecouque C., De Clercq E., et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol.121, pp.58-70, 2016 (Journal Indexed in SCI)
Articles Published in Other Journals
2021
2021Evaluation of molnupiravir analogues as novel coronavirus (SARS-CoV-2) RNA-dependent RNA polymerase (RdRp) inhibitors - an in silico docking and ADMET simulation study
KULABAŞ N. , YEŞİL T. , KÜÇÜKGÜZEL İ.
JOURNAL OF RESEARCH IN PHARMACY, vol.25, no.6, pp.967-981, 2021 (Journal Indexed in ESCI)
2020
2020Synthesis and Anticancer and Antimicrobial Evaluation of Novel Ether-linked Derivatives of Ornidazole
ŞENKARDEŞ S. , Kulabas N. , BİNGÖL ÖZAKPINAR Ö. , Kalayci S., ŞAHİN F., KÜÇÜKGÜZEL İ. , et al.
TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, vol.17, no.1, pp.81-93, 2020 (Journal Indexed in ESCI)
2017
2017Synthesis, characterization and biological evaluation of thioureas, acylthioureas and 4-thiazolidinones as anticancer and antiviral agents
KULABAŞ N. , BİNGÖL ÖZAKPINAR Ö. , ÖZSAVCI D. , Leyssen P., Neyts J., KÜÇÜKGÜZEL İ.
MARMARA PHARMACEUTICAL JOURNAL, vol.21, no.2, pp.371-384, 2017 (Journal Indexed in ESCI)
Refereed Congress / Symposium Publications in Proceedings
2021
2021NOVEL 1,2,4-TRIAZOLES FROM IBUPROFEN AS POTENTIAL mPGES-1 INHIBITORS: SYNTHESIS, IN VITRO AND IN SILICO STUDIES
KULABAŞ N. , Bilgin Y. N. , Çiftçi G., YELEKÇİ K., Gürboğa M., BİNGÖL ÖZAKPINAR Ö. , et al.
13th International Symposium on Pharmaceutical Sciences (ISOPS), Ankara, Turkey, 22 - 25 June 2021
2021
2021Computational Selection of Novel 4-Thiazolidinone Derivatives Containing Benzenesulfonohydrazide Structure as Inhibitors against Mpro and RdRp Of SARS-Cov-2 and Their Predicted ADMET Profiles
Kulabaş N.
INTERNATIONAL CONGRESS ON BIOLOGICAL AND HEALTH SCIENCES, Afyonkarahisar, Turkey, 26 - 28 February 2021, pp.127
2020
2020Computational selection of novel 4-thiazolidinone derivatives containing sulfonamide structure as inhibitors against MPro and RdRp of SARS-CoV-2: A molecular docking study.
KULABAŞ N.
International Eurasian Conference on Biotechnology and Biochemistry (BioTechBioChem 2020), Ankara, Turkey, 16 - 18 December 2020
2019
2019Synthesis, molecular modeling, anticancer and COX-1/2 inhibitory activities of novel thiazolidinones containing benzothiazole core
Tamniku C., KULABAŞ N. , Duracık M., BİNGÖL ÖZAKPINAR Ö. , KÜÇÜKGÜZEL İ.
International Multidisciplinary Symposium on Drug Research Development (DRD 2019), 1 - 03 July 2019, pp.401-403
2018
2018Molecular Modelling Study and Effect of Nitroimidazole Compounds on Proliferation and COX-2 Expression in Prostate Cancer Cells
KULABAŞ N. , ŞENKARDEŞ S. , ÇEVİK Ö., KÜÇÜKGÜZEL İ. , KÜÇÜKGÜZEL Ş. G.
6th International BAU Drug Design Congress, 13 - 15 December 2018
2018
2018A Molecular Modelling Study and Effect of Nitroimidazole Compounds on Proliferation and COX-2 Expression in Prostate Cancer Cells
KULABAŞ N. , ŞENKARDEŞ S. , ÇEVİK Ö., KÜÇÜKGÜZEL İ. , KÜÇÜKGÜZEL Ş. G.
6th BAU Drug Design Congress, 13 - 15 December 2018
2018
2018In silico yöntemlerle seçici COX-2 inhibitörü olabilecek 5-ariliden-4-tiyazolidinon türevlerinin tasarımı, sentezi, anti-HCV, anti-DENV ve COX-1/2 inhibitör etkilerinin incelenmesi
KULABAŞ N. , BİNGÖL ÖZAKPINAR Ö. , Lee J. C. , KÜÇÜKGÜZEL İ.
2. Ulusal Marmara Eczacılık Kongresi, Turkey, 14 - 16 November 2018
2018
2018SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NOVEL ETHER-LINKED DERIVATIVES OF ORNIDAZOLE
Şenkardeş S. , Kulabaş N. , Kalaycı S., Şahin F., Küçükgüzel İ. , Küçükgüzel Ş. G.
12h International Symposium on Pharmaceutical Sciences, Ankara, Turkey, 26 - 29 June 2018, pp.404
2018
2018DESIGN, SYNTHESIS, BIOLOGICAL EVALUATION AND MOLECULAR MODELING STUDIES OF NOVEL 5-ARYLIDENE-4-THIAZOLIDINONES AS SELECTIVE COX-2 INHIBITORS
KULABAŞ N. , BİNGÖL ÖZAKPINAR Ö. , KÜÇÜKGÜZEL İ.
12th International Symposium on Pharmaceutical Sciences (ISOPS-12), 26 - 29 June 2018
2017
2017Computational Design, Synthesis and Antituberculosis Activity of Novel Modified Fluoroquinolone Derivatives
DEMİRCİ A. , KULABAŞ N. , KRISHNA V. S. , SRIRAM D., KÜÇÜKGÜZEL İ.
5th International Bahçeşehir University (BAU) Drug Design Congress, 19 - 21 October 2017
2017
2017SYNTHESIS, CHARACTERIZATION AND BIOLOGICALEVALUATION OF NOVEL THIOETHER DERIVATIVES OF1,2,4-TRIAZOLES AND 1,3,4-OXADIAZOLES AS POTENTIALANTICANCER AGENTS
ERENSOY G., KULABAŞ N. , BİNGÖL ÖZAKPINAR Ö. , TATAR E. , KÜÇÜKGÜZEL İ.
2rd International Gazi Pharma Symposium Series, 11 - 13 October 2017
2017
2017SYNTHESIS, CHARACTERIZATION AND BIOLOGICALEVALUATION OF THIOETHER AND OXIME DERIVATIVES OFIBUPROFEN-BASED 1,2,4-TRIAZOLES AS POTENTIALANTICANCER AGENTS
BÜLBÜL B., KULABAŞ N. , BİNGÖL ÖZAKPINAR Ö. , TATAR E. , KÜÇÜKGÜZEL İ.
2rd International Gazi Pharma Symposium Series, 11 - 13 October 2017
2017
2017DESIGN AND SYNTHESIS OF SOME NOVELFLUOROQUINOLONE DERIVATIVES AS POTENTIALANTIBACTERIAL AND ANTITUBERCULOSIS AGENTS
POYRAZ YILMAZ P., KULABAŞ N. , TATAR E. , BOZDEVECİ A., KRISHNA V. S. , ALPAY KARAOĞLU Ş., et al.
2rd International Gazi Pharma Symposium Series, 11 - 13 October 2017
2017
2017SYNTHESIS, CHARACTERIZATION AND BIOLOGICALEVALUATION OF 5-ARYLIDENE-2-IMINO-1,3-THIAZOLIDINONEDERIVATIVES AS ANTICANCER AGENTS
KULABAŞ N. , BİNGÖL ÖZAKPINAR Ö. , ÖZSAVCI D. , KÜÇÜKGÜZEL İ.
2rd International Gazi Pharma Symposium Series, 11 - 13 October 2017
2017
2017Design, Synthesis and Antibacterial Activitiy of Novel Modified Fluoroquinolone Derivatives
KULABAŞ N. , DEMİRCİ A. , BOZDEVECİ A., ALPAY KARAOĞLU Ş., KÜÇÜKGÜZEL İ.
3 rd International Multidisciplinary Symposium on Drug Research and Development - DRD 2017, Erzurum, Turkey, 5 - 07 October 2017
2017
2017Computer-Aided Design of New Selective COX-2 Inhibitors, Synthesis and Enzyme Inhibition Effects.
KULABAŞ N. , BİNGÖL ÖZAKPINAR Ö. , KÜÇÜKGÜZEL İ.
DRD International Multidisciplinary Symposium on Drug Research and Development, 5 - 07 October 2017
2017
2017Design, Synthesis, Biological Evaluation and Molecular Modeling of Novel 5-Arylidene-4-Thiazolidinones as Potential COX-1/COX-2 Inhibitors
KULABAŞ N. , DEMİRCİ A., BOZDEVECİ A., ALPAY KARAOĞLU Ş., KÜÇÜKGÜZEL İ.
3 rd International Multidisciplinary Symposium on Drug Research and Development - DRD 2017, Erzurum, Turkey, 5 - 07 October 2017
2017
2017Synthesis, Antituberculosis Activity and Molecular Docking Study of Some Novel Fluoroquinolone Derivatives
DEMİRCİ A. , KULABAŞ N. , Dingiş S. İ. , Birgül K., Sriram D., KÜÇÜKGÜZEL İ.
EFMC-ASMC17, 27 - 31 August 2017
2017
2017Synthesis Methods of Ester and Amide Derivatives of NSAIDsand Their Pharmacological Properties
KULABAŞ N. , KÜÇÜKGÜZEL İ.
3. Uluslararası İlaç ve Eczacılık Kongresi, 26 - 29 April 2017
2017
2017Synthesis, Characterization and Biological Evaluation ofThioureas and 4-Thiazolidinones as Anticancer and AntiviralAgents
KULABAŞ N. , BİNGÖL ÖZAKPINAR Ö. , ÖZSAVCI D. , Leyssen P., Neyts J., KÜÇÜKGÜZEL İ.
3. Uluslararası İlaç ve Eczacılık Kongresi, 26 - 29 April 2017
2016
2016Antibakteriyel Etki Göstermeleri Olası Yeni Moksifloksazin Türevlerinin Sentezi ve Moleküler Modelleme Çalışmaları
DEMİRCİ A. , KULABAŞ N. , DİNGİŞ S. İ. , BİRGÜL K., KÜÇÜKGÜZEL İ.
I.Ulusal Marmara Eczacılık Kongresi (UMEK), Turkey, 3 - 05 November 2016
2016
2016Sülfadiazin yapısı taşıyan 5 ariliden 2 imino 1 3 tiyazolidin 4 on türevlerinin sentezi ve karakterizasyonu
SAL A., KULABAŞ N. , KUZNEK F., KÜÇÜKGÜZEL İ.
1. Uusal Marmara Eczacılık Kongresi (UMEK), İstanbul, Turkey, 3 - 05 November 2016
2016
2016Sülfapiridin yapısı taşıyan 5 ariliden 2 imino 1 3 tiyazolidin 4 on türevlerinin sentezi ve karakterizasyonu
KULABAŞ N. , ÇANKAYA C., ZERAY M. Z. , KÜÇÜKGÜZEL İ.
1. Uusal Marmara Eczacılık Kongresi (UMEK), İstanbul, Turkey, 3 - 05 November 2016
2016
2016ANTİBAKTERİYEL ETKİ GÖSTERMELERİ OLASI YENİ MOKSİFLOKSAZİN TÜREVLERİNİN SENTEZİ VE MOLEKÜLER MODELLEME ÇALIŞMALARI
KULABAŞ N. , DEMİRCİ A. , DİNGİŞ S. İ. , BİRGÜL K., KÜÇÜKGÜZEL İ.
1. Uusal Marmara Eczacılık Kongresi (UMEK), İstanbul, Turkey, 3 - 05 November 2016
2016
2016Computational Design,Synthesis and Molecular Properties of Novel Modified Fluoroquinolone Derivatives as Potential Antibacterial and Antituberculosis Agents
DEMİRCİ A. , KULABAŞ N. , DİNGİŞ S. İ. , BİRGÜL K., KÜÇÜKGÜZEL İ.
EFMC-International Symposium on Medicinal Chemistry 2016, 28 August - 01 September 2016
2016
2016Synthesis anti inflammatory activity and molecular modeling studies on cox 1 and cox 2 inhibition of novel amide conjugates of some NSAIDs
KULABAŞ N. , GÜRSOY Ş., ERZİNCAN P., YÜCE DURSUN B., AKTAY G., ERDEM S. , et al.
17th TETRAHEDRON SYMPOSIUM : Challenges in Biological, Bioorganic & Medicinal Chemistry, Sitges, Spain, 28 June - 01 July 2016
2015
2015Molecular Modeling Studies on COX 1 and COX 2 Inhibition of Novel Amide Conjugates of Some NSAIDs with Anti inflammatory Activity
KULABAŞ N. , ERZİNCAN P., DANIŞ Ö. , ERDEM S. , OGAN A. , KÜÇÜKGÜZEL İ.
International Symposium on Drug Research & Development, Turkey, 15 - 17 October 2015
2015
2015Synthesis antiproliferative and apoptosis inducing activity of some novel N 5 aryloxymethyl 4 benzyl 4H 1 2 4 triazole 3 ylthio acetanilides
KULABAŞ N. , TATAR E. , BİNGÖL ÖZAKPINAR Ö. , ÖZSAVCI D. , KÜÇÜKGÜZEL İ.
11th International Symposium on Pharmaceutical Sciences., 9 - 12 June 2015
2014
2014Design Synthesis and Molecular Modeling Studies on Novel Fluoroquinolones as Potential DNA Gyrase Inhibitors
KULABAŞ N. , DEMİRCİ A. , KÜÇÜKGÜZEL İ.
4th International Meeting on Pharmacy and Pharmaceutical Sciences, 18 - 21 September 2014
2014
2014Synthesis and Antituberculosis Evaluation of 1 2 4 Triazole Derivatives Carrying Thioacetic Amide Structure
Kulabaş N. , Tatar E. , Küçükgüzel İ. , Öktem Okullu S., Ünübol N., Kocagöz Z. T.
4th International Meeting on Pharmacy & Pharmaceutical Sciences IMPPS-4, İstanbul, Turkey, 18 - 21 September 2014
2014
2014DESIGN SYNTHESIS AND BIOLOGICAL EVALUATION OF POTENTIAL AMIDE PRODRUGS OF SOME NSAIDs
KULABAŞ N. , SET İ., KÜÇÜKGÜZEL İ. , AKTAY G., GÜRSOY Ş.
50th International Conference on Medicinal Chemistry, Rouen, France, 2 - 04 June 2014
2013
2013Synthesis Characterization and In Vitro Hydrolysis Studies on Potential Amide Prodrugs of Some NSAIDs
SET İ., KULABAŞ N. , KÜÇÜKGÜZEL İ.
International Multidisciplinary Symposium on Drug ResearchDevelopment, Antalya, Turkey, 28 - 30 November 2013
2012
2012Olası Antiviral Etkili 4H 1 2 4 Triazol 3 Tiyoasetamit Türevlerinin Sentezi ve Antiviral Etkilerinin Değerlendirilmesi
KULABAŞ N. , KÜÇÜKGÜZEL İ. , TATAR E. , DE CLERCQ E., ANDREI G., SNOECK R., et al.
3. Ulusal Farmasötik Kimya Kongresi, Malatya, Turkey, 14 - 16 September 2012
2010
2010Synthesis and antiviral evaluation of 2 4 benzyl 5 substituted 4H 1 2 4 triazol 3 yl sulfanyl N substitutedphenyl acetamide derivatives
Kulabaş N. , Küçükgüzel İ. , Tatar E. , De Clercq E., Andreı G., Snoeck R., et al.
3rd International Meeting on Pharmacy & Pharmaceutical Sciences, İstanbul, Turkey, 9 - 12 June 2010
2010
2010Sytnhesis and Antiviral Evaluation of 2 4 Benzyl 5 Substituted 4H 1 2 4 Triazol 3 yl Sulfanyl N Substitutedphenyl Acetamide derivatives
KULABAŞ N. , KÜÇÜKGÜZEL İ. , TATAR E. , DE CERCQ E., ANDREI G., SNOECK R., et al.
Third International Meeting on Pharmacy and Pharmaceutical Sciences (IMPPS-3), İstanbul, Turkey, 9 - 12 June 2010
Supported Projects
2019 - 2021
2019 - 2021Design, synthesis of selective COX-2 inhibitor thiazolidinone derivatives with molecular modeling approach and investigation of antiproliferative effects on MCF-7 cell line
Project Supported by Higher Education Institutions
Kulabaş N. (Executive) , Küçükgüzel İ. , Bingöl Özakpınar Ö.
2018 - 2020
2018 - 2020Synthesis of New Fluoroquinolone Hybrid Molecules with Green Chemistry Techniques and Molecular Docking Methods, Investigation of DNA Gyrase, Topoisomerase IV Inhibition and Antibacterial Activities
TUBITAK Project
(Project Final Report)
Demirbaş A.(Executive), Kulabaş N. , Akdemir A., Bayrak H., Faiz Ö., Kılıç A. O.
2017 - 2019
2017 - 2019Synthesis and investigation of anticancer activity of some 1,2,4-triazole / 1,3,4-oxadiazole compounds containing thioether moiety
Project Supported by Higher Education Institutions
Tatar E. (Executive) , Küçükgüzel İ. , Bingöl Özakpınar Ö. , Kulabaş N. , Bülbül B., Çakır Erensoy G.
2015 - 2017
2015 - 2017Synthesis of amide derivatives of some nonsteroidal antiinflammatory drugs and evaluation of potential prodrugs
Project Supported by Higher Education Institutions
Küçükgüzel İ. (Executive) , Ogan A. , Aktay G., Erdem S. , Danış Ö. , Kulabaş N. , et al.
2014 - 2016
2014 - 2016Synthesis of 2-imino/thioxo-4-thiazolidinone derivatives with potential antivairal/antibacterial effect
Project Supported by Higher Education Institutions
Küçükgüzel İ. (Executive) , Kulabaş N.
Scientific Refereeing
January 2021
January 2021JOURNAL OF RESEARCH IN PHARMACY (ONLINE)
National Scientific Refreed Journal
January 2020
January 2020JOURNAL OF RESEARCH IN PHARMACY (ONLINE)
National Scientific Refreed Journal
December 2019
December 2019TURKİSH JOURNAL OF PHARMACEUTİCAL SCİENCES
National Scientific Refreed Journal
March 2019
March 2019bioorganic chemistry
Other Journals
January 2019
January 2019JOURNAL OF RESEARCH IN PHARMACY (ONLINE)
National Scientific Refreed Journal
January 2018
January 2018JOURNAL OF RESEARCH IN PHARMACY (ONLINE)
National Scientific Refreed Journal
December 2017
December 2017Journal of research in pharmacy (online)
National Scientific Refreed Journal
Awards
June 2018
June 2018Best Poster Presentation
12Th International Symposium On Pharmaceutical Sciences
June 2015
June 2015Best Poster Presentation
11Th International Symposium On Pharmaceutical Sciences
Scholarships
2014 - 2015
2014 - 2015