Supported Projects
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2021 - 2024 Rational design of Corynebacterium glutamicum for a microbial cell factory to synthesize L-DOPA and bioprocess development for L-DOPA production
TÜBİTAK International Bilateral Joint Cooperation Program Project
Sariyar Akbulut B. (Executive), Sayar N. A., Özbek Sarica P., Kazan D.
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2021 - 2024 Replacing food-competing feedstocks with Methanol, CO2 and Methylamine for a Sustainable Bioeconomy
TÜBİTAK International Multi-Cooperation Project
Sariyar Akbulut B. (Executive), Sayar N. A., Özbek Sarica P.
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2020 - 2023 Inhibition and characterization of the inhibition dynamics of the type 4 pili protein complex
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2020 - 2022 Peptidlerle ilişkili bağışıklık sistemi proteinlerinin çalışma mekanizmalarının aydınlatılması
Project Supported by Other Official Institutions
Özbek Sarıca P. (Executive), Sarıyar Akbulut B.
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2019 - 2020 Determination of the hidden pockets in beta-lactamase for allosteric regulation using correlated amino acids
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2018 - 2020 Evaluation of thymol and carvacrol as efflux pumps inhibitors for Staphylococcus aureus
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2016 - 2020 Biosimilar Ranibizumab: Its domestic development and production
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2017 - 2019 Evaluation of the alkaloids of the aporphine family as inhibitors of different efflux pumps using in vitro and in silico methods
Project Supported by Higher Education Institutions
Sarıyar Akbulut B. (Executive), Özbek Sarıca P., Avci F. G.
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2017 - 2018 L-DOPA production in Corynebacterium glutamicum using a metabolic engineering approach
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2014 - 2017 Biophysical characterization of the intracellular localization and celullar transport of inhibitor/antimicrobial peptides
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2014 - 2017 Determination of intracellular targets of different alkaloids with antimicrobial properties by real-time polymerase chain reaction and microarray technologies
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2014 - 2017 Systems Biology Approach for Integrative OMICs Data Analysis to Investigate the Action of Antimicrobial Agents
TÜBİTAK International Bilateral Joint Cooperation Program Project
Sarıyar Akbulut B. (Executive), Kazan D., Sayar N. A.
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2013 - 2014 Investigation of the effect of the allosteric site of β-lactamase for ligand recognition and binding
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2010 - 2012 Extremophiles as a source of natural products for biotechnological applications: Investigation of their osmoregulation strategies using Engineering Principles
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2009 - 2012 Investigation of the cell-uptake and in-vivo inhibition potential of inhibitory peptides using computational and experimental methods
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2008 - 2012 Production of Industrial Enzymes For Feed Industry
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2009 - 2011 The analysis of metabolic capabilities under stress conditions using biosystems engineering principles
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2009 - 2010 Peptide based inhibitor design against beta-lactamase
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2005 - 2007 Investigation of thermostable glucose isomerase export from the the cells using the bacterial Sec and Tat mechanisms
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2003 - 2006 Investigation of halophilic and extremely halophilic archaea isolated from salty environments and the investigation of their extremozymes with a focus on their proteases