Biography
In 2014, I started my master's education in the Department of Bioengineering at Marmara University. In February 2016, I started to work as a teaching assistant in Marmara University Bioengineering Department. In 2017, I completed my master's degree with the thesis titled "Understanding alkaliphilic adaptation of Bacillus marmarensis sp. nov. using omic tools". In 2018, I started my PhD studies at Marmara University, Department of Bioengineering. In April 2024, I successfully passed my thesis defense and was awarded the title of PhD. Since February 2024, I have been continuing my academic studies and contributing to education by giving various courses in the department as an Assistant Professor.
Education
2018 - 2024
2018 - 2024Doctorate
Marmara University, Institute for Graduate Studies in Pure and Applied Sciences, Department of Bioengineering (Eng), Turkey
2022 - 2023
2022 - 2023Doctorate
Eberhard Karls Universitaet Tübingen, Faculty of Science , Computational Systems Biology, Germany
2014 - 2017
2014 - 2017Postgraduate
Marmara University, Institute for Graduate Studies in Pure and Applied Sciences, Biyomühendislik (Yl) (Tezli), Turkey
2010 - 2014
2010 - 2014Undergraduate
Marmara University, Faculty of Engineering, Bioengineering, Turkey
Dissertations
2024
2024Doctorate
An Enhanced Approach for a Systems-Based Metabolic Analysis of Corynebacterium glutamicum
Marmara University, Institute For Graduate Studies İn Pure And Applied Sciences
2017
2017Postgraduate
Understanding alkaliphilic adaptation of B. marmarensis sp. nov. using proteomic tools 
Marmara University, Institute for Graduate Studies in Pure and Applied Sciences, Department of Bioengineering (Eng)
Foreign Languages
C1 Advanced
C1 AdvancedEnglish
Research Areas
Engineering and Technology
Journal articles indexed in SCI, SSCI, and AHCI
2023
2023Can Genome Sequencing Coupled to Flux Balance Analyses Offer Precision Guidance for Industrial Strain Development? The Lessons from Carbon Trafficking in Corynebacterium glutamicum ATCC 21573
Kurpejović E., Wibberg D., Bastem G. M., Burgardt A., Busche T., Kaya F. E., et al.
Omics : a journal of integrative biology
, vol.27, no.9, pp.434-443, 2023 (SCI-Expanded)
2022
2022Can DapC be the missing aminotransferease in the arogenate route of L-tyrosine biosynthesis in Corynebacterium glutamicum?
ALTINIŞIK KAYA F. E., Kurpejovic E., Burgardt A., Wendisch V. F., SARIYAR AKBULUT B.
FEBS OPEN BIO
, vol.12, pp.180-181, 2022 (SCI-Expanded)
2020
2020Identification of novel inhibitors of the ABC transporter BmrA
Serçinoğlu O., Senturk D., Altinisik K., Avci F., Frlan R., Tomašič T., et al.
BIOORGANIC CHEMISTRY
, vol.105, 2020 (SCI-Expanded)
2018
2018What Are the Multi-Omics Mechanisms for Adaptation by Microorganisms to High Alkalinity? A Transcriptomic and Proteomic Study of a Bacillus Strain with Industrial Potential
ALTINIŞIK KAYA F. E., Avci F. G., SAYAR N. A., KAZAN D., SAYAR A. A., SARIYAR AKBULUT B.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
, vol.22, no.11, pp.717-732, 2018 (SCI-Expanded)
2018
2018Targeting a hidden site on class A beta-lactamases
Avci F. G., ALTINIŞIK KAYA F. E., Karacan I., Karagoz D. S., Ersahin S., Eren A., et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
, vol.84, pp.125-133, 2018 (SCI-Expanded)
2017
2017Transcriptomic analysis displays the effect of (-)-roemerine on the motility and nutrient uptake in Escherichia coli
Ayyildiz D., ARĞA K. Y., Avci F. G., ALTINIŞIK KAYA F. E., Gurer C., Toplan G. G., et al.
CURRENT GENETICS
, vol.63, no.4, pp.709-722, 2017 (SCI-Expanded)
2016
2016An evolutionarily conserved allosteric site modulates beta-lactamase activity
Avci F. G., ALTINIŞIK KAYA F. E., Vardar Ulu D., ÖZKIRIMLI ÖLMEZ E., SARIYAR AKBULUT B.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, vol.31, pp.33-40, 2016 (SCI-Expanded)
Articles Published in Other Journals
2021
2021Evaluation of silibinin as an efflux pump inhibitor in Bacillus subtilis
Kaya F. E., Atas B., Avci F. G.
International Journal of Secondary Metabolite
, vol.8, no.2, pp.104-112, 2021 (Scopus)
Papers Presented at Peer-Reviewed Scientific Conferences
2020
2020New inhibitors of the BmrA pump identified through virtual screening
Senturk D., SERÇİNOĞLU O., ALTINIŞIK KAYA F. E., Frlan R., Tomasic T., AVCI F. G., et al.
MuTaLig COST ACTION CA15135 4th WG meeting, 05 March 2020, (Summary Text)
2019
2019Understanding the metabolic reprogramming behind alkaliphilic adaptation in Bacillus marmarensis through a multi-omics data integration strategy
Altınışık F. E., Arğa K. Y., Kazan D., Sarıyar Akbulut B.
44th FEBS Congress: From molecules to living systems, Krakow, Poland, 6 - 11 July 2019, (Summary Text)
2016
2016Understanding alkaliphilic adaptation ofB marmarensis sp nov
ALTINIŞIK F. E., AVCI F. G., DENİZCİ A. A., KAZAN D., SARIYAR AKBULUT B.
FEBS 2016, 3 - 08 September 2016, vol.283, pp.127-427, (Summary Text)
2016
2016Investigation of proteome profile ofalkaliphilic B marmarensis sp nov underdifferent pH conditions
ALTINIŞIK F. E., AVCI F. G., DENİZCİ A. A., KAZAN D., SARIYAR AKBULUT B.
FEBS BIOINTERACTOMICS, 17 - 20 May 2016
2015
2015Mutations of a conserved tryptophan residue of the TEM-1 beta-lactamase
ALTINIŞIK KAYA F. E., Avci F. G., SARIYAR AKBULUT B., ÖZKIRIMLI ÖLMEZ E., Ulu D. V., Karacan I., et al.
29th Annual Symposium of the Protein-Society, Barcelona, Spain, 22 - 25 July 2015, vol.24, pp.175, (Summary Text)
2015
2015A Novel Approach to Deliver Peptides that Target Intracellular Enzymes
ALAYBEYOĞLU B., ALTINIŞIK E., IRVALI D., SARIYAR AKBULUT B., ÖZKIRIMLI ÖLMEZ E.
3rd INTERNATIONALBAU-DRUG DESIGN CONGRESS, İstanbul, Turkey, 1 - 03 October 2015, (Summary Text)
2015
2015Mutations of a conserved tryptophan residue of the TEM 1 ß lactamase
ALTINIŞIK E., AVCI F. G., SARIYAR AKBULUT B., ÖZKIRIMLI ÖLMEZ E., VARDAR D., KARACAN İ., et al.
The 29th Annual Meeting of the Protein Society, 22 - 25 July 2015, pp.294
Mobility Activity
2022 - 2023
2022 - 2023