Serum 25-hydroxyvitamin D concentrations in obese and non-obese women with polycystic ovary syndrome

Yildizhan R., KURDOĞLU M., Adali E., Kolusari A., YILDIZHAN B., Şahin H. G., ...Daha Fazla

Archives of Gynecology and Obstetrics, cilt.280, sa.4, ss.559-563, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 280 Sayı: 4
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1007/s00404-009-0958-7
  • Dergi Adı: Archives of Gynecology and Obstetrics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.559-563
  • Anahtar Kelimeler: 25-Hydroxyvitamin D, Insulin resistance, Non-obese, Obese, Polycystic ovary syndrome
  • Marmara Üniversitesi Adresli: Evet

Özet

Purpose: To investigate the correlation between serum 25-hydroxyvitamin D (25-OH-VD) concentrations and metabolic parameters in obese and non-obese women with polycystic ovary syndrome (PCOS). Methods: One hundred women with PCOS were divided into two groups, obese and non-obese, according to their body mass index (BMI). Waist-to-hip ratio (WHR), Ferriman-Gallwey score, homeostasis model assessment of insulin resistance (HOMA-IR), total cholesterol, triglycerides, calcium, 25-OH-VD, LH/FSH, total testosterone, and DHEAS were measured. Results: The serum 25-OH-VD mean levels were 56.31% lower in the obese PCOS patients. There was an association of increased HOMA-IR, BMI, WHR, triglycerides, total testosterone, and DHEAS with decreased 25-OH-VD concentrations in the obese PCOS patients. Conclusion: Low serum 25-OH-VD concentrations result from the presence of obesity and insulin resistance. However, the dependency between PCOS and hypovitaminosis D is questionable. Hypovitaminosis D should be kept in mind while managing obese women with PCOS. © 2009 Springer-Verlag.