Applications of Chemistry in Nanosciences and Biomaterials Engineering NanoBioMat 2025 – Winter Edition, Bucuresti, Romanya, 26 - 28 Kasım 2025, ss.121-122, (Özet Bildiri)
In the context of green chemistry, nanoparticles have effectively facilitated the biosynthesis of various bioactive compounds present in plant extracts. Terminalia chebula is a plant with versatile medicinal and pharmacological properties and is known as the "King of Medicine” [1]. In this study, inhibitory effects of Ag, Zn and Ag-Zn nanoparticles (NPs) as reducing and stabilizing agents from ethanol extract of Terminalia chebula against microorganisms were evaluated by the agar well diffusion method [2]. Ag-Zn NPs formed an inhibition zone of 20.86 mm against Acinetobacter baumannii and 28.36 mm against Candida tropicalis. The study results showed that both Ag- and Zn-based monometallic nanoparticles exhibited inhibitory activity, while the bimetallic Ag/Zn nanoparticle formulation exhibited superior performance. This performance is attributed to the synergistic effect of the combination of two different metals coexisting on the surface.