Effect of intravenous immunoglobulin on steroid consumption in patients with severe asthma: A double-blind, placebo-controlled, randomized trial

Salmun L., Barlan I., Wolf H., Eibl M., Twarog F., Geha R., ...Daha Fazla

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, cilt.103, sa.5, ss.810-815, 1999 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 103 Sayı: 5
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1016/s0091-6749(99)70424-0
  • Dergi Adı: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.810-815
  • Anahtar Kelimeler: asthma, intravenous immunoglobulin, steroids, LYMPHOCYTE-T ACTIVATION, BRONCHOALVEOLAR LAVAGE, THROMBOCYTOPENIC PURPURA, BRONCHIAL BIOPSIES, KAWASAKI-DISEASE, CHILDHOOD ASTHMA, CELL ACTIVATION, GAMMA-GLOBULIN, ATOPIC ASTHMA, PATHOGENESIS
  • Marmara Üniversitesi Adresli: Hayır

Özet

Background: There is a significant group of patients with severe asthma who require chronic use of systemic steroids for control of their disease. These patients are at risk for severe side effects from oral steroids. Intravenous immunoglobulin. (IVIG) has immunomodulatory properties, and a few open-label trials have suggested its possible benefit in individuals with severe asthma.