Biliary precipitation during ceftriaxone therapy: frequency and risk factors

Soysal A., Erasov K., Akpinar I., Bakir M.

TURKISH JOURNAL OF PEDIATRICS, vol.49, no.4, pp.404-407, 2007 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 4
  • Publication Date: 2007
  • Journal Name: TURKISH JOURNAL OF PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.404-407
  • Marmara University Affiliated: Yes

Abstract

Ceftriaxone, a third-generation cephalosporin, is widely used for treating infection during childhood. It is mainly eliminated in the urine, but approximately 40% of a given dose is unmetabolized and secreted into bile. The aim of this study was to investigate the frequency, clinical characteristics, and outcome of biliary sludge (BS) in addition to potential contributing risk factors in children who receive ceftriaxone.