Effect of BCG vaccination on risk of Mycobacterium tuberculosis infection in children with household tuberculosis contact: a prospective community-based study

Soysal A., Millington K., Bakir M., Dosanjh D., Aslan Y., Deeks J., ...More

LANCET, vol.366, no.9495, pp.1443-1451, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 366 Issue: 9495
  • Publication Date: 2005
  • Doi Number: 10.1016/s0140-6736(05)67534-4
  • Journal Name: LANCET
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1443-1451
  • Marmara University Affiliated: No

Abstract

Background Little is known about factors that affect the risk of acquiring infection in children exposed to Mycobacterium tuberculosis. The effect of BCG vaccination has been difficult to ascertain because the tuberculin skin test (TST), until recently the only method for detecting M tuberculosis infection, does not reliably distinguish between tuberculosis infection and BCG vaccination.