alpha-lipoic acid protects against renal ischaemia-reperfusion injury in rats

Sehirli O., Sener E., Cetinel U., Yueksel M., Gedik N., Sener G.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, cilt.35, sa.3, ss.249-255, 2008 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 3
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1111/j.1440-1681.2007.04810.x
  • Dergi Adı: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.249-255
  • Anahtar Kelimeler: cytokines, ischaemia-reperfusion, kidney, alpha-lipoic acid, myeloperoxidase, ISCHEMIA/REPERFUSION INJURY, SUPEROXIDE-DISMUTASE, OXIDATIVE STRESS, REACTIVE OXYGEN, FREE-RADICALS, AGED RATS, FAILURE, ANTIOXIDANT, MYELOPEROXIDASE, INFLAMMATION
  • Marmara Üniversitesi Adresli: Evet

Özet

1. Oxygen free radicals are important components involved in the pathophysiological processes observed during ischaemia-reperfusion (I/R). The present study was designed to assess the possible protective effect of et-lipoic acid (ALA) on renal I/R injury.