Akademik Veri Yönetim Sistemi
Pamukkale Medical Journal, cilt.13, sa.2, ss.415-423, 2020 (Scopus)
Purpose: The aim of this study was to determine the prevalence of benign and malignant tumors in acromegaly patients in a single center. Materials and methods: Records of 92 patients with acromegaly were retrospectively reviewed. Main clinical characteristics of the patients and characteristics and frequency of benign and malignant tumors were evaluated. Results: Median age of patients was 51 (26-83) years, 52 (56.5%) were female and 40 (43.5%) were male. 4.3% (n=4) of the patients had a malignancy. All malignancies were thyroid papillary carcinoma. 76.1% of the patients had at least one benign tumor. Of patients underwent specific imaging modalities, thyroid nodules was present in 76% (n=57) of patients who underwent thyroid ultrasography (n=74), colon polyps was present in 21.4% (n=15) of patients who underwent colonoscopy (n=70), gallbladder polyps were present in 5.5% (n = 4) of patients who underwent abdominal ultrasonography (n=72) and benign breast lesions were found in 11.5% (n=6) of women who underwent breast imaging (n=52). Conclusion: There is an increased risk of thyroid nodules and thyroid cancer in patients with acromegaly. Therefore, acromegaly patients should be actively monitored for thyroid nodules, and if suspicious findings are detected on ultrasonography, they should be evaluated further.