Protective effects of spironolactone against hepatic ischemia/reperfusion injury in rats

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atalay s., Soylu b., AYKAÇ A., VELİOĞLU ÖĞÜNÇ A., ÇETİNEL Ş., ÖZKAN N., ...Daha Fazla

TURKISH JOURNAL OF SURGERY, cilt.35, sa.4, ss.285-292, 2019 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 4
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5578/turkjsurg.4340
  • Dergi Adı: TURKISH JOURNAL OF SURGERY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.285-292
  • Anahtar Kelimeler: Hepatic ischemia reperfusion, spironolactone, malondialdehyde, glutathione, cytokines, ISCHEMIA-REPERFUSION INJURY, MELATONIN PROTECTS, LIVER-INJURY, RECEPTORS, APOPTOSIS
  • Marmara Üniversitesi Adresli: Evet

Özet

Objective: In the present study, it was aimed to study the antioxidant effects of spironolactone (SPL) to determine its possible protective effects in hepatic ischemia reperfusion injury.