Protective effects of spironolactone against hepatic ischemia/reperfusion injury in rats

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atalay s., Soylu b., AYKAÇ A., VELİOĞLU ÖĞÜNÇ A., ÇETİNEL Ş., ÖZKAN N., ...More

TURKISH JOURNAL OF SURGERY, vol.35, no.4, pp.285-292, 2019 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.5578/turkjsurg.4340
  • Journal Name: TURKISH JOURNAL OF SURGERY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.285-292
  • Keywords: Hepatic ischemia reperfusion, spironolactone, malondialdehyde, glutathione, cytokines, ISCHEMIA-REPERFUSION INJURY, MELATONIN PROTECTS, LIVER-INJURY, RECEPTORS, APOPTOSIS
  • Open Archive Collection: AVESIS Open Access Collection
  • Marmara University Affiliated: Yes

Abstract

Objective: In the present study, it was aimed to study the antioxidant effects of spironolactone (SPL) to determine its possible protective effects in hepatic ischemia reperfusion injury.