Cryptococcus meningitis presented with multiple cerebral infarcts in an immunocompetent patient

ERTÜRK ŞENGEL B., TİGEN E., Sarinoglu R. C., MİDİ İ., ÇERİKÇİOĞLU N., ODABAŞI Z.

IDCASES, cilt.24, 2021 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.idcr.2021.e01154
  • Dergi Adı: IDCASES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Anahtar Kelimeler: Cerebral infarct, Cryptococcus neoformans, Film array, Hydrocephalus, NEGATIVE PATIENTS, NEOFORMANS, INFECTION
  • Marmara Üniversitesi Adresli: Evet

Özet

Cryptococcus neoformans is generally observed with immunosuppressive conditions. Rarely, it may be seen in immunocompetent individuals and presented with non-specific conditions. We described an immunocompetent case of cryptococcal meningitis presented with multiple cerebral infarcts. Despite the late diagnosis and emergence of hydrocephalus during treatment, the patient was recovered without any sequelae. In immunocompetent patients, the conventional diagnostics tests may be negative because of the low fungal load. If it is available, the Biofire FilmArray meningitis panel has high sensitivity and specificity for diagnosis. (C) 2021 The Authors. Published by Elsevier Ltd.