The aim of this study was to compare, under varying conditions, the dentin shear bond strength (SBS) of three solvent-containing (acetone, ethanol, and water) self-etch adhesive with acetone-containing self-etch adhesive and ethanol/water-containing self-etch adhesive. One-hundred non-carious molar teeth were divided into 10 groups of ten specimens each. Kerr Optibond All-In-One (containing acetone, ethanol, and water), Ivoclar Tetric N-Bond Universal (containing ethanol and water), and Shofu BeautiBond (containing acetone) were used as adhesives. The comparisons were made only between adhesives containing common solvents. Three bulk-fill resin composites, Kerr Sonicfill 2, Ivoclar Tetric N-Ceram Bulk Fill, and Shofu Beautifil-Bulk, were chosen for preparation of two-millimeter blocks of composites. Specimens were tested in a universal testing machine (Shimadzu, Japan) in shear to failure at 0.5 mm/min. The shear bond strengths were tested under two conditions: immediately and after 10,000 thermal cycling. The mean values were compared using analysis of variance (ANOVA]. A significance level of p < 0.05 was used in all tests. Failures were categorized into four classes: adhesive failure, cohesive failure in dentin, cohesive failure in the composite, and mix-type failure. Tetric N-Ceram Bulk Fill + Tetric N-Bond Universal showed the highest SBS values both two conditions. The megapascal pressure unit (MPa) was 19.38 (+/- 3.06) in immediate group, while the MPa after thermocycle aging was 10.68 (+/- 2.5]. The SBS of three solvent-containing adhesives was not affected by the content of bulk-fill composites. After thermal aging, there was a significant decrease in the SBS of all groups.