Antifibrotic Effect of Boric Acid in Rats with Epidural Fibrosis

BOZKURT H., Bektasoglu P. K. , Borekci A., Ozturk O. C. , Kertmen H., Egilmez R., ...Daha Fazla

WORLD NEUROSURGERY, cilt.122, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier


BACKGROUND: Epidural fibrosis is a major problem after spine surgery, with some patients having recurrent symptoms secondary to excessive formation of scar tissue resulting in neurologic compression. We used a rat laminectomy model to determine if topical application of boric acid could be helpful in the prevention of epidural fibrosis.