Recent Progress on Synthesis and Aritioance Activity of 4-Th azolidinone


ŞENKARDEŞ S., KÜÇÜKGÜZEL Ş. G.

MINI-REVIEWS IN ORGANIC CHEMISTRY, vol.13, no.5, pp.377-388, 2016 (SCI-Expanded) identifier

  • Publication Type: Article / Review
  • Volume: 13 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.2174/1570193x13666180826154159
  • Journal Name: MINI-REVIEWS IN ORGANIC CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.377-388
  • Keywords: 4-Thiazolidinone, anticancer activity, cytotoxic, diflunisal, etodolac, flurbiprofen, synthesis, ONE-POT SYNTHESIS, MICROWAVE-ASSISTED SYNTHESIS, BIOLOGICAL-ACTIVITIES, THIAZOLIDINONE DERIVATIVES, NONNUCLEOSIDE INHIBITORS, HYDRAZIDE DERIVATIVES, ANTIOXIDANT ACTIVITY, MOLECULAR DOCKING, ANTICANCER, 4-THIAZOLIDINONES
  • Marmara University Affiliated: Yes

Abstract

4-Thiazolidinones are sulphur analogues of oxazolidines. They are heterocyclic ring systems which have been explored for their antimicrobial, anticancer, anti-HCV, antifungal, anticonvulsant, antituberculosis, and other activities. While some earlier reviews on the biological activities of this ring system have been reported, the present review describes more recent synthetic strategies and medicinal aspects of 4-thiazolidinones as anticancer agents reported during the past few years (2010-2016).