Decreasing incidence and severity of Behçet’s disease: a changing trend in epidemiological spectrum possibly associated with oral health

Mumcu G., Alibaz Ö., Ergun S. A. T., Direskeneli R. H.

Turkish journal of medical sciences, vol.50, no.SI-2, pp.1587-1590, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: SI-2
  • Publication Date: 2020
  • Doi Number: 10.3906/sag-2003-147
  • Journal Name: Turkish journal of medical sciences
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1587-1590
  • Keywords: Behget's disease, epidemiology, oral health, INTRAOCULAR INFLAMMATION, INFECTIOUS ETIOLOGY, CLINICAL-FEATURES, 3 DECADES, UVEITIS, MANIFESTATIONS, PREVALENCE, NATIONWIDE, PATTERNS, DIETARY
  • Marmara University Affiliated: Yes

Abstract

This work is licensed under a Creative Commons Attribution 4.0 International License.Behçet’s disease (BD) is a systemic and inflammatory disorder that is mainly present along the ancient Silk Road, from the Mediterranean Sea to East Asia. A wide range of prevalence figures (0.1–420/100,000) have been reported for BD, also among Turkish populations of similar genetic background living in different countries. Recently, a decline in the incidence of BD and a change of the disease spectrum to less-severe manifestations have been reported from Japan and Korea, two genetically homogenous, affluent populations with limited immigration. It was hypothesized that a decline in infectious diseases, especially dental/periodontal infections, associated with the improvement in oral health, could be a part of these changes in the disease expression. Further epidemiological studies in other populations might demonstrate whether there is a worldwide similar trend and may provide a better understanding of the triggering factors for the onset and course of BD.