IFN-gamma stimulation of dental follicle mesenchymal stem cells modulates immune response of CD4(+) T lymphocytes in Der p1(+) asthmatic patients in vitro

Genç, D; Zibandeh, N; Nain, E; Arığ, Ü; Göker, K; Aydıner, ELİF; Akkoç, TUNÇ

doi:10.1016/j.aller.2018.12.005

IFN-gamma stimulation of dental follicle mesenchymal stem cells modulates immune response of CD4(+) T lymphocytes in Der p1(+) asthmatic patients in vitro

Genç D., Zibandeh N., Nain E., Arığ Ü., Göker K., Aydıner E., ...Daha Fazla

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, cilt.47, sa.5, ss.467-476, 2019 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 47 Sayı: 5
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.aller.2018.12.005
Dergi Adı: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.467-476
Anahtar Kelimeler: Dental follicle mesenchymal stem cells, Asthma, House dust mite, Der p1, INTERFERON-GAMMA, COCKROACH ALLERGEN, INFLAMMATION, EPITHELIUM, PATHOLOGY, EXPOSURE, CHILDREN
Marmara Üniversitesi Adresli: Evet

Özet

Background: House dust mite (Dermataphagoides pteronyssinus) is a widespread risk factor in the development of asthma. CD4(+) T lymphocytes have an important role in the pathogenesis of allergic asthma by polarizing to Th2 cells.