Akademik Veri Yönetim Sistemi
İstanbul Medical Journal, cilt.27, sa.1, ss.88-94, 2026 (ESCI, TRDizin)
Introduction: Effective postoperative pain control is essential for recovery. Peripheral nerve blocks, such as the infraclavicular brachial plexus block, are widely used in multimodal analgesia, but their efficacy may be influenced by systemic inflammation. This study evaluated the predictive value of preoperative neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) for block efficacy and postoperative pain in upper extremity surgery. Methods: A retrospective cohort of 116 American Society of Anesthesiologists I–II patients (aged 18–93 years) undergoing surgery under an infraclavicular block was analyzed. Preoperative NLR and PLR were calculated from routine blood counts, and patients were stratified into “high” and “low” inflammation groups. Postoperative pain was assessed using the numeric rating scale (NRS) at 1, 6, 12, and 24 hours; tramadol use was recorded. Block success was evaluated by assessing sensory and motor functions. Results: High NLR and PLR were associated with significantly higher NRS scores at 12 and 24 hours (p<0.001), greater tramadol use (p<0.001), shorter motor block duration, and earlier return of movement. Conclusion: Elevated preoperative NLR and PLR predict reduced infraclavicular block efficacy and greater postoperative pain. These simple, cost-effective biomarkers may aid preoperative risk stratification and guide personalized analgesic strategies.