Circulating vaspin levels and epicardial adipose tissue thickness are associated with impaired coronary flow reserve in patients with nonalcoholic fatty liver disease

YILMAZ Y., Kurt R., Gurdal A., ÖZEN ALAHDAB Y., Yonal O., Senates E., ...Daha Fazla

ATHEROSCLEROSIS, cilt.217, sa.1, ss.125-129, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 217 Sayı: 1
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.atherosclerosis.2011.03.026
  • Dergi Adı: ATHEROSCLEROSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.125-129
  • Anahtar Kelimeler: Biomarkers, Epicardial fat thickness, Coronary flow reserve, Adipokines, Nonalcoholic fatty liver disease, METABOLIC SYNDROME, SERUM-LEVELS, CHEST-PAIN, ARTERY, CHEMERIN, WOMEN, ECHOCARDIOGRAPHY, INFLAMMATION, MARKER, RISK
  • Marmara Üniversitesi Adresli: Evet

Özet

Background: Patients with nonalcoholic fatty liver disease (NAFLD) have a reduced coronary flow reserve (CFR) and an increased risk of cardiovascular disease. The fat cells that surround coronary arteries may play a central and underrecognized role in development of cardiovascular disease through the systemic secretion of adipokines. We therefore evaluated the relation of epicardial fat thickness, serum levels of epicardial fat-related adipokines (chemerin and vaspin), and CFR in patients with NAFLD.