Circulating vaspin levels and epicardial adipose tissue thickness are associated with impaired coronary flow reserve in patients with nonalcoholic fatty liver disease

YILMAZ Y. , Kurt R., Gurdal A., ÖZEN ALAHDAB Y. , Yonal O., Senates E., ...Daha Fazla

ATHEROSCLEROSIS, cilt.217, ss.125-129, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier


Background: Patients with nonalcoholic fatty liver disease (NAFLD) have a reduced coronary flow reserve (CFR) and an increased risk of cardiovascular disease. The fat cells that surround coronary arteries may play a central and underrecognized role in development of cardiovascular disease through the systemic secretion of adipokines. We therefore evaluated the relation of epicardial fat thickness, serum levels of epicardial fat-related adipokines (chemerin and vaspin), and CFR in patients with NAFLD.