Use of T Cell-Based Diagnosis of Tuberculosis Infection to Optimize Interpretation of Tuberculin Skin Testing for Child Tuberculosis Contacts

Bakir M., Dosanjh D. P. S., Deeks J. J., Soysal A., Millington K. A., Efe S., ...More

CLINICAL INFECTIOUS DISEASES, vol.48, no.3, pp.302-312, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 3
  • Publication Date: 2009
  • Doi Number: 10.1086/595847
  • Journal Name: CLINICAL INFECTIOUS DISEASES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.302-312
  • Marmara University Affiliated: Yes

Abstract

Background. Treatment of recent tuberculosis infection in children aged ! 2 years is essential, because of high risk of progression to disease, but diagnosis is hindered by the inaccuracy of the tuberculin skin test (TST). More-accurate T cell-based tests of infection could enhance diagnosis by optimizing interpretation of the TST results.