The markers of bone turnover in patients with lung cancer

DANE F., Turk H. M., Sevinc A., Buyukberber S., Camci C., Tarakcioglu M.

JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION, cilt.100, sa.4, ss.425-428, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 100 Sayı: 4
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/s0027-9684(15)31276-1
  • Dergi Adı: JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.425-428
  • Anahtar Kelimeler: lung cancer, deoxypyridinoline, bone metastasis, bone turnover markers, PROSTATE-CANCER, METABOLIC MARKERS, CARBOXYTERMINAL TELOPEPTIDE, BIOCHEMICAL MARKERS, CROSS-LINKING, METASTASIS, COLLAGEN, DIAGNOSIS, PYRIDINOLINE, RESORPTION
  • Marmara Üniversitesi Adresli: Evet

Özet

Introduction: Bone metastases may change the primary treatment modality, especially if the bone is the only site of metastasis in patients considered to be in the early stage of lung cancer. It is usually diagnosed by imaging techniques. However, the diagnostic yields of imaging methods are limited. Some bone markers such as propeptides of type-1 collagen, pyridinoline cross-links and deoxypyridinoline (D-PYD) cross-links, serum osteocalcin, alkaline phosphatase are thought to be useful in the detection of bone metastasis in lung cancer. Thus, we aimed to determine the clinical usefulness of bone turnover markers in the assessment of bone metastases in patients with lung cancer.