Urinary NGF, TGF-beta 1, TIMP-2 and Bladder Wall Thickness Predict Neurourological Findings in Children with Myelodysplasia

Sekerci Ç. A., Isbilen B., Isman F., Akbal C., ŞİMŞEK F., TARCAN T.

JOURNAL OF UROLOGY, cilt.191, sa.1, ss.199-205, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 191 Sayı: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.juro.2013.08.025
  • Dergi Adı: JOURNAL OF UROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.199-205
  • Anahtar Kelimeler: nerve growth factor, neural tube defects, tissue inhibitor of metalloproteinase-2, transforming growth factor beta1, urinary bladder, neurogenic, NERVE GROWTH-FACTOR, OVERACTIVE BLADDER, TRANSFORMING GROWTH-FACTOR-BETA-1, MATRIX METALLOPROTEINASES, ULTRASOUND ASSESSMENT, JUNCTION OBSTRUCTION, DETRUSOR THICKNESS, SMOOTH-MUSCLE, INHIBITORS
  • Marmara Üniversitesi Adresli: Evet

Özet

Purpose: Dimercapto-succinic acid scintigraphy and urodynamic studies are gold standards to evaluate renal scarring and neurogenic bladder dysfunction, respectively. We sought to establish the value of bladder wall thickness together with urine NGF, TGF-beta 1 and TIMP-2 to predict the urodynamic profile and upper urinary tract damage in children with myelodysplasia.