Protective effect of melatonin against ischemia/reperfusion-induced oxidative remote organ injury in the rat


Kacmaz A., User E., Sehirli A., Tilki M., Ozkan S., Sener G.

SURGERY TODAY, cilt.35, sa.9, ss.744-750, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Konu: 9
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1007/s00595-005-3027-2
  • Dergi Adı: SURGERY TODAY
  • Sayfa Sayıları: ss.744-750

Özet

Purpose. Oxygen free radicals are considered to be important components involved in the pathophysiological tissue alterations observed during ischemia/reperfusion (I/R). Based on the potent antioxidant effects of melatonin, we investigated the putative protective role of melatonin against I/R-induced oxidative remote organ injury.