Effect of angiotensin-converting enzyme inhibition on endothelial function and insulin sensitivity in hypertensive patients

Tezcan H., Yavuz D., Toprak A., Akpinar I., Koc M., Deyneli O., ...Daha Fazla

JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM, cilt.4, sa.2, ss.119-123, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 4 Sayı: 2
  • Basım Tarihi: 2003
  • Doi Numarası: 10.3317/jraas.2003.012
  • Dergi Adı: JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.119-123
  • Anahtar Kelimeler: ACE inhibition, endothelial dysfunction, insulin sensitivity, DEPENDENT DIABETES-MELLITUS, ACE-INHIBITION, II ANTAGONISM, DYSFUNCTION, RESISTANCE, DISEASE, MECHANISMS, SYSTEM, VASODILATION, IMPROVEMENT
  • Marmara Üniversitesi Adresli: Evet

Özet

Introduction Evidence suggests an association between insulin resistance, hypertension and impaired endothelial function. Studies have shown that insulin resistance precedes the development of hypertension. By improving insulin sensitivity, it may be possible to improve hypertension and the subsequent damage to vessel walls. Some data indicates beneficial effects of angiotensin-converting enzyme (ACE) inhibitors on insulin sensitivity and endothelial function. We aimed to investigate these effects of ACE inhibition in the same group of patients with essential hypertension.