BMC Oral Health, cilt.26, sa.1, 2026 (SCI-Expanded, Scopus)
Background/purpose: This retrospective observational case series aimed to evaluate the clinical and digital (photographic) success rate of CAD/CAM hybrid composite indirect restorations used on molar- incisor hypomineralisation affected first permanent molars (FPMs) after 12 months." Materials and methods: A total ofnine children (mean age: 11.62 ± 1.26 years) with MIH- affected FPMs (receiving a score of 2c or 4c according to the MIH-TNI classification) received 13 CAD/CAM indirect hybrid composite restorations. Restorations were assessed after a follow-up period of twelve months. Anatomic form, marginal adaptation, marginal discoloration, color match, surface texture, restoration fracture, and secondary caries were assessed both clinically and digitally through intraoral photographs, according to modified United States Public Health Service criteria. Descriptive and exploratory analyse were conducted, including the McNemar Chi-square test. The significance level used in the statistical analysis (p < 0.05). Results: The survival rate of the restorations was 100% after 12 months. According to the USPHS evaluation criteria, the majority of restorations were scored as Alpha. Specifically, for color match, 10 restorations (77%) were rated Alpha and 3 (23%) as Bravo at the 12-month evaluation. The difference in color match scores between baseline and 12 months was statistically significant (p= 0.025). For marginal discoloration, scores decreased from 100% Alpha at baseline to 12 (92%) Alpha and 1 (8%) Bravo at the 12-month follow-up. A statistically significant difference was also found between baseline and 12-month scores for marginal discoloration (p = 0.025). Conclusion: The findings highlight the potential of CAD/CAM restorations as a reliable treatment option for MIH-affected FPMs, particularly in cases with severe structural compromise. However, these results need to be confirmed through long-term randomized controlled clinical trials with larger cohorts, double-blinded protocols, and longer follow-up periods.