Effects of captopril and losartan on lipid peroxidation, protein oxidation and nitric oxide release in diabetic rat kidney.

Yavuz D. , Kucukkaya B., Haklar G. , Ersoz O., Akoglu E., Akalin S.

Prostaglandins, leukotrienes, and essential fatty acids, cilt.69, sa.4, ss.223-7, 2003 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 69 Konu: 4
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1016/s0952-3278(03)00088-7
  • Dergi Adı: Prostaglandins, leukotrienes, and essential fatty acids
  • Sayfa Sayıları: ss.223-7

Özet

Increased oxidative stress has an important role in the pathogenesis of diabetic nephropathy. The aim of this study was to evaluate the effects of renin-anigiotensin system blockage, either by angiotensin-converting enzyme inhibition or angiotensin receptor blockage, on oxidative stress and nitric oxide release in diabetic rat kidneys.