Effects of captopril and losartan on lipid peroxidation, protein oxidation and nitric oxide release in diabetic rat kidney.


Yavuz D., Kucukkaya B., Haklar G., Ersoz O., Akoglu E., Akalin S.

Prostaglandins, leukotrienes, and essential fatty acids, cilt.69, sa.4, ss.223-7, 2003 (SCI-Expanded) identifier identifier identifier

Özet

Increased oxidative stress has an important role in the pathogenesis of diabetic nephropathy. The aim of this study was to evaluate the effects of renin-anigiotensin system blockage, either by angiotensin-converting enzyme inhibition or angiotensin receptor blockage, on oxidative stress and nitric oxide release in diabetic rat kidneys.