Effects of captopril and losartan on lipid peroxidation, protein oxidation and nitric oxide release in diabetic rat kidney.

Yavuz, DİLEK; Kucukkaya, B; Haklar, GONCAGÜL; Ersoz, O; Akoglu, E; Akalin, S

doi:10.1016/s0952-3278(03)00088-7

Effects of captopril and losartan on lipid peroxidation, protein oxidation and nitric oxide release in diabetic rat kidney.

Yavuz D. , Kucukkaya B., Haklar G. , Ersoz O., Akoglu E., Akalin S.

Prostaglandins, leukotrienes, and essential fatty acids, vol.69, no.4, pp.223-7, 2003 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 69 Issue: 4
Publication Date: 2003
Doi Number: 10.1016/s0952-3278(03)00088-7
Title of Journal : Prostaglandins, leukotrienes, and essential fatty acids
Page Numbers: pp.223-7

Abstract

Increased oxidative stress has an important role in the pathogenesis of diabetic nephropathy. The aim of this study was to evaluate the effects of renin-anigiotensin system blockage, either by angiotensin-converting enzyme inhibition or angiotensin receptor blockage, on oxidative stress and nitric oxide release in diabetic rat kidneys.