Effects of captopril and losartan on lipid peroxidation, protein oxidation and nitric oxide release in diabetic rat kidney.


Yavuz D. , Kucukkaya B., Haklar G. , Ersoz O., Akoglu E., Akalin S.

Prostaglandins, leukotrienes, and essential fatty acids, vol.69, no.4, pp.223-7, 2003 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 69 Issue: 4
  • Publication Date: 2003
  • Doi Number: 10.1016/s0952-3278(03)00088-7
  • Title of Journal : Prostaglandins, leukotrienes, and essential fatty acids
  • Page Numbers: pp.223-7

Abstract

Increased oxidative stress has an important role in the pathogenesis of diabetic nephropathy. The aim of this study was to evaluate the effects of renin-anigiotensin system blockage, either by angiotensin-converting enzyme inhibition or angiotensin receptor blockage, on oxidative stress and nitric oxide release in diabetic rat kidneys.