Effects of captopril and losartan on lipid peroxidation, protein oxidation and nitric oxide release in diabetic rat kidney.

Yavuz, DİLEK; Kucukkaya, B; Haklar, GONCAGÜL; Ersoz, O; Akoglu, E; Akalin, S

doi:10.1016/s0952-3278(03)00088-7

Effects of captopril and losartan on lipid peroxidation, protein oxidation and nitric oxide release in diabetic rat kidney.

Yavuz D., Kucukkaya B., Haklar G., Ersoz O., Akoglu E., Akalin S.

Prostaglandins, leukotrienes, and essential fatty acids, cilt.69, sa.4, ss.223-7, 2003 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 69 Sayı: 4
Basım Tarihi: 2003
Doi Numarası: 10.1016/s0952-3278(03)00088-7
Dergi Adı: Prostaglandins, leukotrienes, and essential fatty acids
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.223-7
Marmara Üniversitesi Adresli: Evet

Özet

Increased oxidative stress has an important role in the pathogenesis of diabetic nephropathy. The aim of this study was to evaluate the effects of renin-anigiotensin system blockage, either by angiotensin-converting enzyme inhibition or angiotensin receptor blockage, on oxidative stress and nitric oxide release in diabetic rat kidneys.