An evaluation of the efficacy of a topical gel with Triester Glycerol Oxide (TGO) in the treatment of minor recurrent aphthous stomatitis in a Turkish cohort: A randomized, double-blind, placebo-controlled clinical trial

Ofluoglu D., Ergun S., Warnakulasuriya S., Namdar-Pekiner F. M., Tanyeri H.

MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL, vol.22, no.2, 2017 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.4317/medoral.21469
  • Journal Name: MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Topical therapy, triester glycerol oxide, triamcinolone acetonide, minor recurrent aphthous stomatitis, MANAGEMENT, ULCERATION, TABLETS, DISEASE, ULCERS, LASER, PASTE
  • Marmara University Affiliated: Yes

Abstract

Background: Triester glycerol oxide gel (Protefix (R) Queisser Pharma, Germany) is a new topical agent that has the property of adherence to the oral mucosa by forming a lipid film which protects against mechanical trauma and may help to reduce oral tissue moisture loss and inflammation. The aim of this clinical trial was to determine the efficacy of a topical TGO gel and to also compare it with triamcinolone acetonide pomade in the treatment of minor recurrent aphthous stomatitis.