An evaluation of the efficacy of a topical gel with Triester Glycerol Oxide (TGO) in the treatment of minor recurrent aphthous stomatitis in a Turkish cohort: A randomized, double-blind, placebo-controlled clinical trial

Ofluoglu D., Ergun S., Warnakulasuriya S., Namdar-Pekiner F. M., Tanyeri H.

MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL, cilt.22, sa.2, 2017 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.4317/medoral.21469
  • Dergi Adı: MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Topical therapy, triester glycerol oxide, triamcinolone acetonide, minor recurrent aphthous stomatitis, MANAGEMENT, ULCERATION, TABLETS, DISEASE, ULCERS, LASER, PASTE
  • Marmara Üniversitesi Adresli: Evet

Özet

Background: Triester glycerol oxide gel (Protefix (R) Queisser Pharma, Germany) is a new topical agent that has the property of adherence to the oral mucosa by forming a lipid film which protects against mechanical trauma and may help to reduce oral tissue moisture loss and inflammation. The aim of this clinical trial was to determine the efficacy of a topical TGO gel and to also compare it with triamcinolone acetonide pomade in the treatment of minor recurrent aphthous stomatitis.