Spectrophotometrıc Investıgatıon Of Metal Complexes With Clonidine Hydrochloride


Bayraktar S., Karaderi S. , Mazı C.

1ST INTERNATIONAL BALKAN CHEMISTRY CONGRESS (IBCC2018-Edirne)., Edirne, Türkiye, 17 - 20 Eylül 2018, cilt.1, ss.68

  • Cilt numarası: 1
  • Basıldığı Şehir: Edirne
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.68

Özet

Hypertension is defined as a cardiovascular disease or high blood pressure. High blood pressure can be

decreased by hypertensive agents [1]. For instance, Clonidine hydrochloride provides to decrease high blood

pressure to normal levels. At the same time, narcotics are used to alleviate withdrawal symptoms associated with

the long-term use of alcohol, benzodiazepine and nicotine (smoking) [2,3]. In this study, the metal complex

studies were investigated on related with copper and magnesium for Clonidine hydrochloride. In accordance to

the studies, the intake of Clonidine hydrochloride may lead to formation of chelates with metals. This is

significant in terms of biological activity of microorganisms. The metal complex ratios were determined by UVVis

Spectrophotometric method with using mol ratio method for Cu-Clonidine hydrochloride and Mg-Clonidine

hydrochloride. And also, structures of the metals complexes are supported by spectrophotometric method. The

experimental data indicate the formation of metal:ligant 1:1 complexes for Cu-Clonidine hydrochloride and Mg-

Clonidine Hydrochloride.