Value of 68Ga-DOTATATE PET/CT in Follow-up of Renal Cell Carcinoma with Multiple Atypical Metastatic Sites

Filizoglu N., ÖZGÜVEN S., ÖNEŞ T., TUROĞLU H. T., ERDİL T. Y.

Clinical Nuclear Medicine, vol.49, no.12, 2024 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 12
  • Publication Date: 2024
  • Doi Number: 10.1097/rlu.0000000000005493
  • Journal Name: Clinical Nuclear Medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Keywords: DOTATATE, metastases, PET/CT, renal cell carcinoma
  • Marmara University Affiliated: Yes

Abstract

The development of late metastatic recurrence after nephrectomy is a well-known characteristic of renal cell carcinoma (RCC). Correct diagnosis is often challenging due to the long time between primary tumor excision and the development of metastases. 68Ga-DOTATATE PET/CT has the potential to be employed in the follow-up of RCC, because RCC expresses somatostatin receptors. However, limited cases have been reported demonstrating 68Ga-DOTATATE uptake in the metastases of RCC. Herein, we describe a unique case of RCC with multiple atypical metastatic sites, emphasizing the usefulness of 68Ga-DOTATATE PET/CT in the evaluation and follow-up of patients with RCC.