Protective role of resveratrol against cisplatin induced ototoxicity in guinea pigs

YUMUŞAKHUYLU A. C., Yazici M., Sari M., Binnetoglu A., Kosemihal E., Akdas F., ...More

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, vol.76, no.3, pp.404-408, 2012 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 76 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.1016/j.ijporl.2011.12.021
  • Journal Name: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.404-408
  • Keywords: Resveratrol, Cisplatin, Ototoxicity, Auditory brainstem response, Reactive oxygen species, Scanning electron microscopy, ROUND WINDOW APPLICATION, D-METHIONINE, HAIR-CELLS, VITAMIN-E, ANTIOXIDANT, NEPHROTOXICITY, EXPRESSION, GROWTH, RATS
  • Marmara University Affiliated: Yes

Abstract

Objective: The aim of this study was to evaluate the effectiveness of systemic administration of resveratrol against cisplatin-induced ototoxicity in guinea pigs.