Resveratrol reduces renal and lung injury caused by sepsis in rats

Kolgazi M., Sener G., Cetinel S., Gedik N., Alican I.

JOURNAL OF SURGICAL RESEARCH, cilt.134, sa.2, ss.315-321, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 134 Sayı: 2
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.jss.2005.12.027
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.315-321
  • Anahtar Kelimeler: sepsis, antioxidant, kidney, lung, rat, resveratrol, WINE CONSTITUENT POLYPHENOL, RED WINE, INFLAMMATION, DAMAGE, ISCHEMIA/REPERFUSION, CARDIOPROTECTION, ANTIOXIDANTS, PERITONITIS, GLUTATHIONE, EXPRESSION
  • Marmara Üniversitesi Adresli: Evet

Özet

Resveratrol (3,5,4'-trans-trihydroxystilbene), a natural phytoalexin, has various pharmacological effects, including anti-inflammatory properties via inhibition of oxidation, leukocyte priming, and expression of inflammatory mediators. The present study was aimed to investigate the possible beneficial activities of resveratrol on lung and kidney damage in a rat model of sepsis.