The effect of tocopheryl phosphates on atherosclerosis progression in rabbits fed with a high cholesterol diet

Negis Y., Aytan N., Ozer N., Ogru E., Libinaki R., Gianello R., ...Daha Fazla

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, cilt.450, sa.1, ss.63-66, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 450 Sayı: 1
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.abb.2006.02.027
  • Dergi Adı: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.63-66
  • Anahtar Kelimeler: tocopherol, antioxidants, atherosclerosis, tocopheryl phosphate, VITAMIN-E, GENE-EXPRESSION, PROTEIN
  • Marmara Üniversitesi Adresli: Evet

Özet

The effect of tocopheryl phosphate on atherosclerosis progression has been studied in rabbits, fed with a 2% cholesterol diet and compared with an equivalent amount of alpha-tocopheryl acetate. The results show that the atherosclerotic-preventing effect of the phosphate derivative was more pronounced than that of the acetate derivative. alpha-Tocopheryl phosphate was also more potent in diminishing the expression of CD36 than the acetate derivative. (c) 2006 Elsevier Inc. All rights reserved.