Circulating endothelial cells are associated with future vascular events in hemodialysis patients

Koc M., Richards H., Bihorac A., Ross E., Schold J., Segal M.

KIDNEY INTERNATIONAL, cilt.67, sa.3, ss.1078-1083, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 67 Sayı: 3
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1111/j.1523-1755.2005.00173.x
  • Dergi Adı: KIDNEY INTERNATIONAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1078-1083
  • Anahtar Kelimeler: circulating endothelial cells, hemodialysis, dysfunctional endothelium, inflammation, PROGENITOR CELLS, CARDIOVASCULAR-DISEASE, RISK-FACTORS, MORTALITY, MORBIDITY, ATHEROSCLEROSIS, HYPOALBUMINEMIA, CARDIOMYOPATHY, INTERLEUKIN-6, HYPERTENSION
  • Marmara Üniversitesi Adresli: Evet

Özet

Background. Endothelial dysfunction and injury are thought to have a key role in the pathogenesis of cardiovascular disease. We hypothesized that the presence of circulating endothelial cells, as a reflection of ongoing endothelial injury, might provide a novel means for predicting cardiovascular events in hemodialysis subjects who are known to be at marked increased risk for cardiovascular disease.