Expression of the chemokine receptor CXCR2 in normal and neoplastic neuroendocrine cells


Tecimer T., Dlott J., Chuntharapai A., Martin A., Peiper S.

ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, cilt.124, ss.520-525, 2000 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 124 Konu: 4
  • Basım Tarihi: 2000
  • Dergi Adı: ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
  • Sayfa Sayıları: ss.520-525

Özet

Background-Chemokines effect their proinflammatory and growth regulatory roles through interaction with serpentine receptors. One such receptor, CXCR2, binds multiple CXC chemokines, including interleukin 8, GRO-alpha,, CRO-beta, GRO-gamma, and NAP-2, We have previously identified CXCR2 expression on myeloid cells, notably mature granulocytes, and projection neurons.