Expression of the chemokine receptor CXCR2 in normal and neoplastic neuroendocrine cells

Tecimer T., Dlott J., Chuntharapai A., Martin A., Peiper S.

ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, vol.124, no.4, pp.520-525, 2000 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 124 Issue: 4
  • Publication Date: 2000
  • Journal Name: ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.520-525
  • Marmara University Affiliated: No

Abstract

Background-Chemokines effect their proinflammatory and growth regulatory roles through interaction with serpentine receptors. One such receptor, CXCR2, binds multiple CXC chemokines, including interleukin 8, GRO-alpha,, CRO-beta, GRO-gamma, and NAP-2, We have previously identified CXCR2 expression on myeloid cells, notably mature granulocytes, and projection neurons.