The relationship between heparanase levels, thrombus burden and thromboembolism in patients receiving unfractionated heparin treatment for prosthetic valve thrombosis

Bayam E., KALÇIK M., Gurbuz A. S. , Yesin M., Guner A., Gunduz S., ...More

THROMBOSIS RESEARCH, vol.171, pp.103-110, 2018 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 171
  • Publication Date: 2018
  • Doi Number: 10.1016/j.thromres.2018.09.061
  • Title of Journal : THROMBOSIS RESEARCH
  • Page Numbers: pp.103-110


Introduction: Procoagulant activity of heparanase has been recently described in several arterial and venous thrombotic disorders. In this study, we aimed to investigate the role of heparanase with regard to thrombus burden, thromboembolism, and treatment success with unfractionated heparin (UFH) in patients with prosthetic valve thrombosis (PVT).