Akademik Veri Yönetim Sistemi
Journal of Clinical Urology, 2025 (ESCI)
Introduction: Benign prostatic obstruction (BPO) causes lower urinary tract symptoms (LUTS) in ageing males, often linked to benign prostatic hyperplasia (BPH). While conservative treatments provide temporary relief, surgical interventions like transurethral resection of the prostate (TURP) offer long-term solutions. Holmium yytrium-aluminium-garnet (YAG) laser enucleation of the prostate (HoLEP) has emerged as a promising alternative to TURP, especially for larger prostate volumes (>80 g). This study aimed to compare the outcomes of HoLEP and TURP in patients with prostates larger and smaller than 80 g. Methods: This retrospective clinical study was conducted at Marmara University Hospital between February 2022 and 2024, involving patients over 50 years of age with BPO who underwent either HoLEP or bipolar TURP. Prostate size was categorised as >80 or <80 g. The primary outcomes were surgical success, operative time, and efficiency, while secondary outcomes included safety, catheter removal time, and long-term complications. Results: HoLEP showed superior results in ∆Qmax, ∆IPSS, resected/enucleated prostate volume, and catheter retrieval time in both prostate size categories. However, TURP had a shorter operation duration. Intraoperative complications were more frequent in the HoLEP group, especially in larger prostates, but postoperative complications were similar in both groups. Conclusion: HoLEP offers better clinical outcomes compared with TURP, regardless of prostate size. Although HoLEP has more intraoperative complications due to its steep learning curve, it is expected to become the gold standard in BPH surgery as experience with the technique increases.