Inhibitory effect of alendronate on bone resorption of autogenous free bone grafts in rats


Altundal H., Sayrak H., Yurtsever E., Goeker K.

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, cilt.65, sa.3, ss.508-516, 2007 (SCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 65 Konu: 3
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.joms.2005.11.054
  • Dergi Adı: JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
  • Sayfa Sayıları: ss.508-516

Özet

Purpose: This study was designed to investigate the effect of alendronate on the resorption of autogenous free bone grafts by biochemical and histopathologic methods. Alendronate is a potent inhibitor of osteoclast-mediated bone resorption with no adverse effect on the mineralization of bone.