Dynamic contrast-enhanced MRI in the differentiation of posttreatment fibrosis from recurrent carcinoma of the head and neck

Oysu A., Ayanoglu E., Kodalli N., Oysu Ç., Uneri C., Erzen C.

CLINICAL IMAGING, vol.29, no.5, pp.307-312, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 5
  • Publication Date: 2005
  • Doi Number: 10.1016/j.clinimag.2005.01.024
  • Journal Name: CLINICAL IMAGING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.307-312
  • Keywords: magnetic resonance imaging, head and neck neoplasms, neoplasm recurrence, local, fibrosis, diagnosis, differential, NASOPHARYNGEAL CARCINOMA, BENIGN CONDITIONS, CANCER, TUMORS, ECHO, SUBTRACTION, RADIATION, IMAGES, CT
  • Marmara University Affiliated: No

Abstract

Objective: The aim of this study was to investigate the value of dynamic contrast-enhanced magnetic resonance imaging (MRI) in the differentiation of posttreatment fibrosis from recurrent carcinoma, by comparing the dynamic contrast-enhancement characteristics of the lesions. Materials and methods: Twenty-six patients with previously treated carcinoma of the head and neck are studied by conventional and dynamic contrast-enhanced MRI at least 6 months after treatment by radiotherapy and/or surgery. Patients are divided into tumor-positive or -negative groups according to the radiological and clinical follow-up and biopsy. Lesion enhancement ratios at each dynamic sequence are calculated. Results: The tumor-positive group consisted of 11 patients, while the tumor-negative group included 15 patients. Between the two groups, lesion enhancement ratios are found to be significantly different (P<.05). Conclusion: Dynamic contrast-enhanced MRI may be a valuable modality in the differentiation of recurrent tumor from posttreatment fibrotic changes of the head and neck. (c) 2005 Elsevier Inc. All rights reserved.