Effects of Ankaferd BloodStopper on dermal healing in diabetic rats

Aktop S., Cevreli B., Genc D., Serdaroglu Kasikci E., Comunoglu Ustundag N., Zibandeh N., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.47, sa.2, ss.675-680, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3906/sag-1604-145
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.675-680
  • Anahtar Kelimeler: Streptozotocin, Ankaferd BloodStopper, glutathione, lipid peroxidation, vascular endothelial growth factor, transforming growth factor-beta, ENDOTHELIAL GROWTH-FACTOR, BLOOD STOPPER, OXIDATIVE STRESS, LIVER, EXPRESSION, SKIN, GLUTATHIONE, MODULATION, TGF-BETA-1, APOPTOSIS
  • Marmara Üniversitesi Adresli: Evet

Özet

Background/aim: Diabetes mellitus inhibits wound-induced angiogenesis, impairs the wound healing process, and leads to the development of chronic wounds. Ankaferd BloodStopper (ABS) is a new and promising local haemostatic agent. Although the mechanism of ABS-mediated haemostasis is well established, little is known about the associated histological and biochemical tissue reactions. The aim of this study was to evaluate the effects of this new-generation local haemostatic agent on short-term soft-tissue healing in streptozotocin (STZ)-treated rats.