Cefaclor, a cephalosporin antibiotic, delays gastric emptying rate by a CCK-A receptor-mediated mechanism in the rat


Bozkurt A., Deniz M., Yegen B.

BRITISH JOURNAL OF PHARMACOLOGY, cilt.131, sa.3, ss.399-404, 2000 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 131 Konu: 3
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1038/sj.bjp.0703585
  • Dergi Adı: BRITISH JOURNAL OF PHARMACOLOGY
  • Sayfa Sayıları: ss.399-404

Özet

1 Studies in vitro suggest that cephalosporin antibiotics release the gut hormone cholecystokinin. Cholecystokinin is known to inhibit gastric emptying. Here we examine the effects of cefaclor on gastric emptying and intestinal motility.