Muir-Torre syndrome

Tuncel A., Çelebiler Ö., ELÇİOĞLU H. N.

European Journal of Plastic Surgery, vol.27, no.5, pp.241-243, 2004 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 5
  • Publication Date: 2004
  • Doi Number: 10.1007/s00238-004-0655-5
  • Journal Name: European Journal of Plastic Surgery
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.241-243
  • Keywords: Mismatch repair genes, Muir-Torre syndrome, Sebaceous neoplasm, Visceral malignancy
  • Marmara University Affiliated: Yes

Abstract

Muir-Torre syndrome is a rare autosomal dominant disorder characterized by sebaceous neoplasms of skin and one or more malignancies of the visceral organs. The sebaceous neoplasms include sebaceous adenoma, sebaceous epithelioma, basal cell epithelioma, and sebaceous carcinoma [1]. Since these sebaceous neoplasms occur rarely, when they are recognized, consideration of Muir-Torre syndrome is important. Recent identification of the main genes made it possible to employ molecular studies in affected patients. A case ultimately diagnosed as Muir-Torre syndrome because of mucoepidermoid carcinoma of the parotid gland, prostate adenocarcinoma and sebaceous cell carcinoma of the upper eyelid will be presented. © Springer-Verlag 2004.