Pediatric saprochaete infections: insights from case reports

Aslan Tuncay, Sevgi; AKKOÇ, GÜLŞEN; Ergenc, Zeynep; Yılmaz, Seyhan; PARLAK, BURCU; DİZİ IŞIK, AYLİN; CANİZCİ ERDEMLİ, PINAR; Buyuktas Aytac, Didem; Abaci Capar, Meryem; Senay, Rabia; Tufan Tas, Burcu; Eker, NURŞAH; Koc, Ahmet; Kepenekli, EDA; Ocal Demir, SEVLİYA

doi:10.1007/s10096-025-05378-0

Pediatric saprochaete infections: insights from case reports

Aslan Tuncay S., AKKOÇ G., Ergenc Z., Yılmaz S., PARLAK B., DİZİ IŞIK A., ...Daha Fazla

European Journal of Clinical Microbiology and Infectious Diseases, 2025 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Basım Tarihi: 2025
Doi Numarası: 10.1007/s10096-025-05378-0
Dergi Adı: European Journal of Clinical Microbiology and Infectious Diseases
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Environment Index, MEDLINE, Public Affairs Index
Anahtar Kelimeler: Fungal infection, Immunocompromised, Neutropenia, Parenchymal nodules
Marmara Üniversitesi Adresli: Evet

Özet

Saprochaete species are emerging fungal pathogens, particularly affecting immunocompromised individuals, with clinical manifestations ranging from superficial to invasive infections. We present three cases of pediatric Saprochaete spp. infections, detailing clinical presentation, diagnostic workup, and treatment strategies. Two patients with acute myeloid leukemia developed bloodstream infections with Saprochaete clavata; both required prolonged antifungal therapy due to deep organ involvement, and one experienced relapse after treatment discontinuation. The third case involved a patient with cystic fibrosis, in whom Saprochaete capitata was isolated from sputum; she improved with antifungal therapy and had no relapse. Saprochaete spp. infections in pediatric populations present diagnostic and therapeutic challenges. Further research is needed to optimize management strategies and improve patient outcomes.