Radiation field size and dose determine oncologic outcome in esophageal cancer

Gemici C., Yaprak G., BATIREL H. F., Ilhan M., Mayadagli A.

WORLD JOURNAL OF SURGICAL ONCOLOGY, cilt.14, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1186/s12957-016-1024-0
  • Dergi Adı: WORLD JOURNAL OF SURGICAL ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Esophageal cancer, Concomitant chemoradiotherapy, Locoregional recurrence, Overall survival, SQUAMOUS-CELL CARCINOMA, POSITRON-EMISSION-TOMOGRAPHY, PHASE-II, PREOPERATIVE CHEMORADIOTHERAPY, NEOADJUVANT CHEMORADIOTHERAPY, CONCURRENT CHEMOTHERAPY, TRANSHIATAL RESECTION, CLINICAL-IMPLICATIONS, RECURRENCE PATTERN, RANDOMIZED-TRIAL
  • Marmara Üniversitesi Adresli: Evet

Özet

Background: Locoregional recurrence is a major problem in esophageal cancer patients treated with definitive concomitant chemoradiotherapy. Approximately half of the patients fail locoregionally. We analyzed the impact of enlarged radiation field size and higher radiation dose incorporated to chemoradiotherapy on oncologic outcome.