Focal segmental glomerulosclerosis associated with idiopathic myelofibrosis.

Kaygusuz I., KOÇ M. , Arikan H. , Adiguzel C., Cakalagaoglu F., Tuglular T. F. , ...More

Renal failure, vol.32, no.2, pp.273-6, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 2
  • Publication Date: 2010
  • Doi Number: 10.3109/08860220903573286
  • Title of Journal : Renal failure
  • Page Numbers: pp.273-6


A patient with idiopathic myelofibrosis with nephrotic syndrome is reported. Seven months after the initial diagnosis of myelofibrosis, the patient was presented with dyspnea, generalized edema, heavy proteinuria, massive pleural effusion, and ascites. Renal biopsy showed focal segmental glomerulosclerosis. After starting immunosuppressive therapy consisting of cyclosporine and steroids, his renal function and proteinuria improved and transfusion requirements decreased.