Octreotide: a new approach to the management of acute abdominal hypertension

Kacmaz A., Polat A., User Y., Tilki M., Ozkan S., Sener G.

PEPTIDES, cilt.24, sa.9, ss.1381-1386, 2003 (SCI İndekslerine Giren Dergi) identifier identifier identifier


Acutely increased intra-abdominal pressure (IAP) may lead to abdominal compartment syndrome (ACS), which ischaemia/reperfusion (I/R) injury plays an important role. The main goal of the management of ACS is to lower the intra-abdominal pressure despite reperfusion injury. Octreotide (OCT), a synthetic somatostatin analogue, lowers the splanchnic perfusion. The aim of this study was to investigate whether OCT improves the reperfusion injury after decompression of acute abdominal hypertension.